GUGGULSTEROLVI

Base Information

• Chemical Name: GUGGULSTEROLVI
• CAS No.: 61391-01-3
• Molecular Formula: C21H32O2
• Molecular Weight: 316.48
• Mol file: 61391-01-3.mol

Synonyms:GUGGULSTEROLVI

Chemical Property of GUGGULSTEROLVI

Chemical Property:

• PSA: 37.30000
• LogP: 4.51530

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of GUGGULSTEROLVI

There total 4 articles about GUGGULSTEROLVI which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Z-guggulsterone (39025-23-5,39025-24-6,95975-55-6) → guggulsterol-VI (61391-01-3,85769-69-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd-SrCO₃ / ethanol / 2 h / 26 °C

2: 1) LAH 2) MnO₂ / 1) THF, 28 deg C, 2 h 2) CHCl₃, room temp., 10 h

With manganese(IV) oxide; lithium aluminium tetrahydride; hydrogen; Pd/SrCO₃; In ethanol;

DOI:10.1016/0040-4020(82)85024-2

Reference yield:

Z-guggulsterone (39025-23-5,39025-24-6,95975-55-6) → 16β-hydroxy-4-pregnen-3-one (61391-01-3,85769-69-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd-SrCO₃ / ethanol / 2 h / 26 °C

2: 1) LAH 2) MnO₂ / 1) THF, 28 deg C, 2 h 2) CHCl₃, room temp., 10 h

With manganese(IV) oxide; lithium aluminium tetrahydride; hydrogen; Pd/SrCO₃; In ethanol;

DOI:10.1016/0040-4020(82)85024-2

Reference yield:

4-pregnene-3,16-dione (85769-68-2) → guggulsterol-VI (61391-01-3,85769-69-3) + 16β-hydroxy-4-pregnen-3-one (61391-01-3,85769-69-3)

Guidance literature:

With (1S)-10-camphorsulfonic acid; manganese(IV) oxide; lithium aluminium tetrahydride; Yield given. Multistep reaction; 1) THF, 28 deg C, 2 h 2) CHCl₃, room temp., 10 h;

DOI:10.1016/0040-4020(82)85024-2

upstream raw materials:

4-pregnene-3,16-dione

Z-guggulsterone

Refernces