2-Naphthyl alpha-D-glucopyranoside

Base Information

• Chemical Name: 2-Naphthyl alpha-D-glucopyranoside
• CAS No.: 25320-79-0
• Molecular Formula: C16H18O6
• Molecular Weight: 306.315
• Hs Code.: 29389090
• European Community (EC) Number: 246-834-0
• DSSTox Substance ID: DTXSID50948165
• Nikkaji Number: J250.427H
• Wikidata: Q27162432
• Mol file: 25320-79-0.mol

Synonyms:2-NA-alpha-glc;2-naphthyl alpha-D-glucopyranoside;2-naphthyl-beta-D-glucoside;2-naphthyl-glucoside;2-naphthylglucoside

Chemical Property of 2-Naphthyl alpha-D-glucopyranoside

Chemical Property:

• Appearance/Colour: White Solid
• Vapor Pressure: 9.78E-14mmHg at 25°C
• Melting Point: 207 ºC ± 2 ºC
• Refractive Index: 1.682
• Boiling Point: 567.9 °C at 760 mmHg
• PKA: 12.80±0.70(Predicted)
• Flash Point: 297.3 °C
• PSA: 99.38000
• Density: 1.454 g/cm³
• LogP: 0.01850
• Storage Temp.: 2-8°C
• Solubility.: Methanol (Slightly)
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 306.11033829
• Heavy Atom Count: 22
• Complexity: 365

Purity/Quality:

98%,99%, ^*data from raw suppliers

b-Naphthyl a-D-Glucopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)OC3C(C(C(C(O3)CO)O)O)O
• Isomeric SMILES: C1=CC=C2C=C(C=CC2=C1)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O
• Uses: Chemotherapeutic agent, especially cancerostatics.

Technology Process of 2-Naphthyl alpha-D-glucopyranoside

There total 7 articles about 2-Naphthyl alpha-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-O-(2′-naphthyl)-2,3,4,6-tetra-O-acetyl-α-D-glucopyranoside (37812-69-4) → [2]naphthyl-α-D-glucopyranoside (25320-79-0)

Guidance literature:

With methanol; sodium methylate;

Reference yield:

β-naphthol (135-19-3) → [2]naphthyl-α-D-glucopyranoside (25320-79-0)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc chloride

2: sodium methylate; methanol

With methanol; sodium methylate; zinc(II) chloride;

Reference yield:

β-D-glucose pentaacetate (604-69-3) → [2]naphthyl-α-D-glucopyranoside (25320-79-0)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc chloride

2: sodium methylate; methanol

With methanol; sodium methylate; zinc(II) chloride;

upstream raw materials:

1-O-(2′-naphthyl)-2,3,4,6-tetra-O-acetyl-α-D-glucopyranoside

β-naphthol

β-D-glucose pentaacetate

2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl chloride