4-Nitrosobenzoic acid ethyl ester

Base Information

• Chemical Name: 4-Nitrosobenzoic acid ethyl ester
• CAS No.: 7476-79-1
• Molecular Formula: C9H9NO3
• Molecular Weight: 179.175
• Hs Code.: 2916399090
• Mol file: 7476-79-1.mol

Synonyms:Ethyl p-nitrosobenzoate;4-Nitroso-benzoesaeure-ethylester;4-Nitroso-benzoesaeure-aethylester;Benzoic acid,p-nitroso-,ethyl ester;4-nitroso-benzoic acid ethyl ester;Benzoic acid,4-nitroso-,ethyl ester;4-nitrozobenzoic acid ethyl ester;

Chemical Property of 4-Nitrosobenzoic acid ethyl ester

Chemical Property:

• Vapor Pressure: 0.00249mmHg at 25°C
• Boiling Point: 287.4°Cat760mmHg
• Flash Point: 137.5°C
• PSA: 55.73000
• Density: 1.16g/cm³
• LogP: 2.26120

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Nitrosobenzoic acid ethyl ester

There total 5 articles about 4-Nitrosobenzoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

p-aminoethylbenzoate (94-09-7) → 4-nitrosobenzoic acid ethyl ester (7476-79-1)

Guidance literature:

With sodium tungstate; phosphoric acid; tetrabutylammomium bromide; dihydrogen peroxide; In dichloromethane; pentane; at 35 - 40 ℃; for 2.5h;

Reference yield: 57.0%

oxo-(N-(C6H5)hydroxylamido-O,N)(pyridine-2,6-dicarboxylato)(hexamethylphosphoramide)molybdenum(VI) → oxoperoxo-(pyridine-2,6-dicarboxylato)(hexamethylphosphoramide)molybdenum(VI) (67584-07-0) + 4-nitrosobenzoic acid ethyl ester (7476-79-1)

Guidance literature:

With H₂O₂; In dichloromethane; water; byproducts: H2O; addn. 2 equiv 35% aq. soln. H2O2 to soln. Mo-complex/CH2Cl2, mixt. left until red-purple col. disappeared (25 min); addn. petroleum ether (pptn.), filtered;

Reference yield:

ethyl 4-nitrobenzoate (99-77-4) → 4-nitrosobenzoic acid ethyl ester (7476-79-1) + 4,4'-azoxy-di-benzoic acid diethyl ester (6421-04-1,34241-38-8)

Guidance literature:

With ethanol; acetic acid; zinc; nachfolgende Behandlung der erhaltenen Loesung des 4-Hydroxylamino-benzoesaeure-aethylesters mit Kaliumdichromat und verd.Schwefelsaeure;

upstream raw materials:

ethyl 4-nitrobenzoate

p-aminoethylbenzoate

4-amino-benzoic acid

Downstream raw materials:

benzil-bis-[N-(4-ethoxycarbonyl-phenyl)-oxime ]

benzoic acid

4,4'-azoxy-di-benzoic acid diethyl ester

4,4'-bis(ethoxycarbonyl)azobenzene

Refernces

• 1、 Zhang, Yuanfei,Chen, Zhe-Ning,Su, Weiping. "Rhodium(III)-catalyzed regioselective C–H nitrosation/annulation of unsymmetrical azobenzenes to synthesize benzotriazole N-oxides via a RhIII/RhIII redox-neutral pathway". supporting information. . Retrieved 2021/05/19.
• 2、 Ieronimo, Gabriella,Palmisano, Giovanni,Maspero, Angelo,Marzorati, Alessandro,Scapinello, Luca,Masciocchi, Norberto,Cravotto, Giancarlo,Barge, Alessandro,Simonetti, Marco,Ameta, Keshav Lalit,Nicholas, Kenneth M.,Penoni, Andrea. "A novel synthesis of N-hydroxy-3-aroylindoles and 3-aroylindoles". supporting information. p. 6853 - 6859. Retrieved 2018/10/20.