Phenol, 2-amino-4-chloro-, hydrogen sulfate (ester)

Base Information

• Chemical Name: Phenol, 2-amino-4-chloro-, hydrogen sulfate (ester)
• CAS No.: 22332-20-3
• Molecular Formula: C6H6 Cl N O4 S
• Molecular Weight: 223.637
• Hs Code.: 2922199090
• UNII: ND9Y2J5KFW
• DSSTox Substance ID: DTXSID6066781
• Nikkaji Number: J285.485F
• Wikidata: Q81993367
• Mol file: 22332-20-3.mol

Synonyms:22332-20-3;Phenol, 2-amino-4-chloro-, hydrogen sulfate (ester);Phenol, 2-amino-4-chloro-, 1-(hydrogen sulfate);ND9Y2J5KFW;DTXSID6066781;EINECS 244-918-1;Sulfuric acid hydrogen 2-amino-4-chlorophenyl ester

Chemical Property of Phenol, 2-amino-4-chloro-, hydrogen sulfate (ester)

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 98.00000
• Density: 1.724g/cm³
• LogP: 2.76580
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 222.9706065
• Heavy Atom Count: 13
• Complexity: 262

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)N)OS(=O)(=O)O

Technology Process of Phenol, 2-amino-4-chloro-, hydrogen sulfate (ester)

There total 1 articles about Phenol, 2-amino-4-chloro-, hydrogen sulfate (ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-aniline (108-42-9) → sulfuric acid mono-(2-amino-4-chloro-phenyl ester) (22332-20-3)

Guidance literature:

With dipotassium peroxodisulfate;

DOI:10.1039/jr9540000980

Reference yield:

sulfuric acid mono-(2-amino-4-chloro-phenyl ester) (22332-20-3) → 2-hydroxy-5-chloro-aniline (95-85-2)

Guidance literature:

With hydrogenchloride;

DOI:10.1039/jr9540000980

Reference yield:

sulfuric acid mono-(2-amino-4-chloro-phenyl ester) (22332-20-3) → 2-benzoylamino-1-benzoyloxy-4-chloro-benzene

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous HCl

With hydrogenchloride;

DOI:10.1039/jr9540000980

upstream raw materials:

3-chloro-aniline

Downstream raw materials:

2-hydroxy-5-chloro-aniline