2-Amino-6-bromopurine

Base Information

• Chemical Name: 2-Amino-6-bromopurine
• CAS No.: 82499-03-4
• Molecular Formula: C5H4BrN5
• Molecular Weight: 214.024
• Hs Code.: 2933990090
• European Community (EC) Number: 806-423-4
• NSC Number: 67618
• DSSTox Substance ID: DTXSID00422006
• Nikkaji Number: J407.772E
• Mol file: 82499-03-4.mol

Synonyms:2-Amino-6-bromopurine;6-bromo-7H-purin-2-amine;82499-03-4;6-bromo-9H-purin-2-amine;1H-Purin-2-amine, 6-bromo-;6-bromo-9H-purin-2-ylamine;6-bromo-1H-purin-2-amine;Purine, 2-amino-6-bromo-;SCHEMBL355361;2-Amino-6-bromopurine, 95%;DTXSID00422006;HPGBGNVPUMCKPM-UHFFFAOYSA-N;NSC67618;BI 104;MFCD01321309;NSC 67618;NSC-67618;AKOS015854820;AM83086;AS-58326

Chemical Property of 2-Amino-6-bromopurine

Chemical Property:

• Vapor Pressure: 2.11E-16mmHg at 25°C
• Melting Point: >350 °C(lit.)
• Refractive Index: 1.851
• Boiling Point: 642.5 °C at 760 mmHg
• PKA: 6.58±0.20(Predicted)
• Flash Point: 342.4 °C
• PSA: 80.48000
• Density: 2.14 g/cm³
• LogP: 1.27880
• Storage Temp.: 2-8°C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 212.96501
• Heavy Atom Count: 11
• Complexity: 154

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-6-bromopurine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=NC2=C(N1)C(=NC(=N2)N)Br

Technology Process of 2-Amino-6-bromopurine

There total 3 articles about 2-Amino-6-bromopurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

→ 2-dimethylaminomethyleneamino-6-bromopurine + 2-amino-6-bromopurine (82499-03-4)

Guidance literature:

Reference yield: 52.0%

phosphoryl(III) bromide (21295-51-2) + 2-amino-1,9-dihydro-6H-purin-6-one (73-40-5) → 2-amino-6-bromopurine (82499-03-4)

Guidance literature:

In ammonium hydroxide; water; N,N-dimethyl-formamide;

Reference yield:

→ 2-amino-6-bromopurine (82499-03-4)

Guidance literature:

2-Amino-6-purin-thiol, Br2, HBr, MeOH, H2O <10grad; 1.5h>;

upstream raw materials:

phosphoryl(III) bromide

2-amino-1,9-dihydro-6H-purin-6-one

Downstream raw materials:

2-{1-[(2-amino-9H-purin-6-yl)amino]propyl}-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one

2-amino-6-phenyl-9H-purine

Refernces