2-Ethoxyethylphosphonic acid diethyl ester

Base Information

• Chemical Name: 2-Ethoxyethylphosphonic acid diethyl ester
• CAS No.: 5191-35-5
• Molecular Formula: C₈H₁₉O₄P
• Molecular Weight: 210.21
• Hs Code.: 2931900090
• Mol file: 5191-35-5.mol

Synonyms:Phosphonic acid,(2-ethoxyethyl)-,diethyl ester;1-(2-diethoxyphosphorylethoxy)ethane;Diethyl ethoxyethyl phosphonate;

Chemical Property of 2-Ethoxyethylphosphonic acid diethyl ester

Chemical Property:

• Vapor Pressure: 0.0146mmHg at 25°C
• Boiling Point: 265.9°Cat760mmHg
• Flash Point: 128.6°C
• PSA: 54.57000
• Density: 1.031g/cm³
• LogP: 2.28900

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Ethoxyethylphosphonic acid diethyl ester

There total 5 articles about 2-Ethoxyethylphosphonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,1-bis(diethylphosphono)ethylene (37465-31-9) → diethyl (2-ethoxyethyl)phosphonate (5191-35-5)

Guidance literature:

With sodium ethanolate; In ethanol; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2005.04.045

Reference yield: 85.0%

ethanol (64-17-5) + 1,1-bis(diethylphosphono)ethylene (37465-31-9) → diethyl (2-ethoxyethyl)phosphonate (5191-35-5)

Guidance literature:

With sodium ethanolate; at 20 ℃; for 16h;

DOI:10.1002/ejoc.200500097

Reference yield: 40.0%

ethanol (64-17-5) + Oxiranylidene-2,2-bis(phosphonic acid) tetraethyl ester (35335-22-9) → diethyl (2-ethoxyethyl)phosphonate (5191-35-5)

Guidance literature:

With sodium ethanolate; at 20 ℃; for 16h;

DOI:10.1002/ejoc.200500097

upstream raw materials:

ethanol

Diethyl vinylphosphonate

2-Bromoethyl ethyl ether

triethyl phosphite

Downstream raw materials:

(2-ethoxy-ethyl)-phosphonic acid ethyl ester-(4-nitro-phenyl ester)

Refernces

• 1、 Nishiwaki,T.. "-". . p. 711 - 722. Retrieved 1966.
• 2、 Szajnman, Sergio H.,Linares, Guadalupe Garcia,Moro, Pablo,Rodriguez, Juan B.. "New insights into the chemistry of gem-bis(phosphonates): Unexpected rearrangement of Michael-type acceptors". . p. 3687 - 3696. Retrieved 2007/10/03.