Ditetradecylamine

Base Information

• Chemical Name: Ditetradecylamine
• CAS No.: 17361-44-3
• Molecular Formula: C28H59N
• Molecular Weight: 409.783
• European Community (EC) Number: 241-389-9
• NSC Number: 91530
• UNII: O13O07DPF4
• DSSTox Substance ID: DTXSID70169638,DTXSID601022396
• Nikkaji Number: J287.023A
• Wikidata: Q27285186
• Mol file: 17361-44-3.mol

Synonyms:Ditetradecylamine;17361-44-3;Dimyristylamine;1-Tetradecanamine, N-tetradecyl-;N-tetradecyltetradecan-1-amine;UNII-O13O07DPF4;O13O07DPF4;EINECS 241-389-9;NSC-91530;NSC91530;di-n-tetradecylamine;Ditetradecylamine, 95%;ALAMINE 205;N,N-DITETRADECYLAMINE;SCHEMBL239733;C28H59N;DTXSID70169638;DTXSID601022396;C28-H59-N;MFCD00026602;NSC 91530;AKOS024429323;BS-15654;CS-0198989;FT-0625368;D81279;Q27285186

Chemical Property of Ditetradecylamine

Chemical Property:

• Vapor Pressure: 1.17E-09mmHg at 25°C
• Melting Point: 60.62°C
• Refractive Index: 1.454
• Boiling Point: 487.6 °C at 760 mmHg
• Flash Point: 170.9 °C
• PSA: 12.03000
• Density: 0.82 g/cm³
• LogP: 10.36910
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 13.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 26
• Exact Mass: 409.464750886
• Heavy Atom Count: 29
• Complexity: 237

Purity/Quality:

99% ^*data from raw suppliers

Ditetradecylamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCNCCCCCCCCCCCCCC

Technology Process of Ditetradecylamine

There total 23 articles about Ditetradecylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

N,N-ditetradecyl-p-toluenesulfonamide → ditetradecylamine (17361-44-3)

Guidance literature:

With naphthalene; naphthalen-1-yl-lithium; In tetrahydrofuran; methanol; water;

Reference yield: 83.0%

tetradecylamine (2016-42-4) + tetradecanoyl chloride (112-64-1) → ditetradecylamine (17361-44-3)

Guidance literature:

tetradecylamine; tetradecanoyl chloride; With dmap; triethylamine; In toluene; at 20 ℃; for 48h;

With lithium aluminium tetrahydride; In tetrahydrofuran; for 18h; Heating;

DOI:10.1039/b417091c

Reference yield: 70.0%

n-tetradecanoic acid (544-63-8) → tetradecylamine (2016-42-4) + ditetradecylamine (17361-44-3) + N-tetradecyltetradecanamide

Guidance literature:

n-tetradecanoic acid; With cyclopentyl methyl ether; ammonia; at 200 ℃; under 4500.45 Torr; Sealed tube; Green chemistry;

With cyclopentyl methyl ether; ammonia; hydrogen; at 200 ℃; for 6.5h; under 42004.2 Torr; Cooling with ice; Green chemistry;

DOI:10.1039/d0gc01441a

upstream raw materials:

tetradecylamine

myristyl chloride

1-Bromotetradecane

tetradecanamide

Downstream raw materials:

methyl-ditetradecyl-amine

2,3-Dimethoxy-N,N-ditetradecyl-terephthalamic acid

N,N-ditetradecyl-Nε-benzyloxycarbonyl-L-lysinamide

N,N-ditetradecyl-Nα-<6-(trimethylammonio)hexanoyl>-Nε-benzyloxycarbonyl-L-lysinamide bromide

Refernces

• 1、 Coeck, Robin,De Vos, Dirk E.. "One-pot reductive amination of carboxylic acids: a sustainable method for primary amine synthesis". supporting information. p. 5105 - 5114. Retrieved 2020/08/25.
• 2、 -. "NUCLEOSIDE-MODIFIED RNA FOR INDUCING AN ADAPTIVE IMMUNE RESPONSE". . . Retrieved 2018/05/24.