Epizizanal

Base Information

• Chemical Name: Epizizanal
• CAS No.: 82463-21-6
• Molecular Formula: C₁₅H₂₂O
• Molecular Weight: 218.339
• Mol file: 82463-21-6.mol

Synonyms:

Chemical Property of Epizizanal

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Epizizanal

There total 6 articles about Epizizanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

epizizanoic alcohol (16223-63-5,52795-49-0,88034-77-9) → 12-oxoepizizaene (82463-21-6)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane;

DOI:10.1016/S0040-4039(00)85675-0

Reference yield:

methyl zizanoate (18444-89-8,26410-02-6) → 12-oxoepizizaene (82463-21-6)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOCH₃ / methanol / Heating

2: LAH

3: PCC / CH₂Cl₂

With lithium aluminium tetrahydride; sodium methylate; pyridinium chlorochromate; In methanol; dichloromethane;

DOI:10.1016/S0040-4039(00)85675-0

Reference yield:

methyl epizizanoate (22387-78-6,26410-02-6) → 12-oxoepizizaene (82463-21-6)

Guidance literature:

Multi-step reaction with 2 steps

1: LAH

2: PCC / CH₂Cl₂

With lithium aluminium tetrahydride; pyridinium chlorochromate; In dichloromethane;

DOI:10.1016/S0040-4039(00)85675-0

upstream raw materials:

epizizanoic alcohol

2,12-epoxyzizaene

(-)-khusimone

8-carboethoxy-4-(2-chloroethyl)-3,3-dimethyl-2-methylidenebicyclo<4.3.0>nonan-7-one

Downstream raw materials:

(+)-zizanoic acid

(-)-epizizanoic acid

zizanal

Refernces

• 1、 Liu, Hsing-Jang,Chan, Wing Hong. "Total synthesis of zizaane sesquiterpenes: (-)-khusimone, (+)-zizanoic acid, and (-)-epizizanoic acid". . p. 1081 - 1091. Retrieved 2007/10/02.