N,N-bis(2-chloroethyl)-2-ethoxyaniline

Base Information

• Chemical Name: N,N-bis(2-chloroethyl)-2-ethoxyaniline
• CAS No.: 27077-12-9
• Molecular Formula: C₁₂H₁₇Cl₂NO
• Molecular Weight: 262.179
• Mol file: 27077-12-9.mol

Synonyms:o-Phenetidine,N,N-bis(2-chloroethyl)- (6CI,7CI,8CI); NSC 18419

Chemical Property of N,N-bis(2-chloroethyl)-2-ethoxyaniline

Chemical Property:

• Vapor Pressure: 0.000169mmHg at 25°C
• Boiling Point: 330.2°Cat760mmHg
• Flash Point: 153.5°C
• Density: 1.171g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-bis(2-chloroethyl)-2-ethoxyaniline

There total 3 articles about N,N-bis(2-chloroethyl)-2-ethoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-bis-(2-hydroxy-ethyl)-o-phenetidine (78987-73-2) → 2-Aethoxy-N.N-bis-<2-chlor-aethyl>-anilin (27077-12-9)

Guidance literature:

With trichlorophosphate;

Reference yield:

ortho-phenitidine (94-70-2) → 2-Aethoxy-N.N-bis-<2-chlor-aethyl>-anilin (27077-12-9)

Guidance literature:

Multi-step reaction with 2 steps

2: POCl₃

With trichlorophosphate;

Reference yield:

→ 2-Aethoxy-N.N-bis-<2-chlor-aethyl>-anilin (27077-12-9)

Guidance literature:

entspr. subst. N,N-Bis-(2-hydroxy-ethyl)-anilin, POCl3;

DOI:10.1021/jm00297a071

upstream raw materials:

N,N-bis-(2-hydroxy-ethyl)-o-phenetidine

ortho-phenitidine

Downstream raw materials:

1-(2-ethoxy-phenyl)-4-(3-methoxy-propyl)-piperazine