3-(10-(2-CARBOXY-ETHYL)-ANTHRACEN-9-YL)-PROPIONIC ACID

Base Information

• Chemical Name: 3-(10-(2-CARBOXY-ETHYL)-ANTHRACEN-9-YL)-PROPIONIC ACID
• CAS No.: 71367-28-7
• Molecular Formula: C20H18 O4
• Molecular Weight: 322.361
• Mol file: 71367-28-7.mol

Synonyms:9,10-Anthracenedipropionicacid (6CI); 3-[10-(2-Carboxyethyl)anthracen-9-yl]propionic acid

Chemical Property of 3-(10-(2-CARBOXY-ETHYL)-ANTHRACEN-9-YL)-PROPIONIC ACID

Chemical Property:

• Melting Point: 244 °C
• Boiling Point: 596.0±30.0 °C(Predicted)
• PKA: 4.29±0.10(Predicted)
• Flash Point: 328.3oC
• PSA: 74.60000
• Density: 1.312±0.06 g/cm3(Predicted)
• LogP: 4.02740
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

3,3'-(Anthracene-9,10-diyl)dipropanoicacid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3-(10-(2-CARBOXY-ETHYL)-ANTHRACEN-9-YL)-PROPIONIC ACID

There total 13 articles about 3-(10-(2-CARBOXY-ETHYL)-ANTHRACEN-9-YL)-PROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

α,α'-(anthracene-9,10-diyl)bis(methylmalonic)acid (307554-62-7) → 3,3'-(anthracene-9,10-diyl)dipropionic acid (71367-28-7)

Guidance literature:

In diphenylether; at 260 ℃; for 48h;

DOI:10.1002/ejoc.201800283

Reference yield: 76.0%

di-tert-butyl 3,3'-(anthracene-9,10-diyl)dipropionate (1225023-89-1) → 3,3'-(anthracene-9,10-diyl)dipropionic acid (71367-28-7)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1039/c001502d

Reference yield:

9,10-bis<<2,2-di(ethoxycarbonyl)>ethyl>anthracene (307554-61-6) → 3,3'-(anthracene-9,10-diyl)dipropionic acid (71367-28-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / methanol; CHCl₃ / 3 h / Heating

2: 120 h / 120 °C

With sodium hydroxide; In methanol; chloroform;

DOI:10.1016/j.tet.2006.08.094

upstream raw materials:

α,α'-(anthracene-9,10-diyl)bis(methylmalonic)acid

9,10-dimethylanthracene

9,10-dibromomethylanthracene

9,10-bis<<2,2-di(ethoxycarbonyl)>ethyl>anthracene

Downstream raw materials:

N,N'-di(2,3-dihydroxypropyl)-9,10-anthracenedipropanamide

9,10-dihydro-N-(4-nitrophenyl)-9,10-(epoxyimino)-11-carbamylanthracene-9,10-dipropanoic acid

(S,S)-di-tert-butyl 2-(3-{10-[2-(1-tert-butoxycarbonylmethyl-2-isopropoxy-ethylcarbamoyl)ethyl]anthracen-9-yl}propionylamino)butanedioate

diethyl 9,10-anthracenedipropionate

Refernces

• 1、 Wang, Haoyan,Li, Wei-Guang,Zeng, Kaixing,Wu, Yan-Jiao,Zhang, Yixin,Xu, Tian-Le,Chen, Yiyun. "Photocatalysis Enables Visible-Light Uncaging of Bioactive Molecules in Live Cells". supporting information. p. 561 - 565. Retrieved 2019/01/04.
• 2、 Matsuo, Kazuya,Nakagawa, Hidehiko,Adachi, Yusuke,Kameda, Eri,Aizawa, Kazuyuki,Tsumoto, Hiroki,Suzuki, Takayoshi,Miyata, Naoki. "Photoinduced upregulation of calcitonin gene-related peptide in A549 cells through HNO release from a hydrophilic photocontrollable HNO donor". experimental part. p. 1055 - 1062. Retrieved 2012/09/25.