5-(Acetylamino)isophthalic acid

Base Information

• Chemical Name: 5-(Acetylamino)isophthalic acid
• CAS No.: 6344-50-9
• Molecular Formula: C10H9NO5
• Molecular Weight: 223.185
• Hs Code.: 2924199090
• Mol file: 6344-50-9.mol

Synonyms:Isophthalicacid, 5-acetamido- (6CI);5-N-Acetylaminoisophthalic acid;NSC 50749;

Chemical Property of 5-(Acetylamino)isophthalic acid

Chemical Property:

• Vapor Pressure: 6.94E-14mmHg at 25°C
• Refractive Index: 1.658
• Boiling Point: 571.167 °C at 760 mmHg
• Flash Point: 299.231 °C
• PSA: 103.70000
• Density: 1.512 g/cm³
• LogP: 1.11440

Purity/Quality:

98%min ^*data from raw suppliers

5-Acetylamino isophthalicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-(Acetylamino)isophthalic acid

There total 8 articles about 5-(Acetylamino)isophthalic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-aminoisophthalic acid (99-31-0) + acetic anhydride (108-24-7) → 5-acetamidebenzene-1,3-dicarboxylic acid (6344-50-9)

Guidance literature:

With acetic acid; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1016/j.tet.2010.05.023

Reference yield: 82.0%

5-aminoisophthalic acid (99-31-0) + tiolacetic acid (507-09-5) → 5-acetamidebenzene-1,3-dicarboxylic acid (6344-50-9)

Guidance literature:

With copper(ll) sulfate pentahydrate; In methanol; at 20 ℃; for 0.0833333h;

DOI:10.1021/jo400701v

Reference yield: 65.0%

5-aminoisophthalic acid (99-31-0) + acetic anhydride (108-24-7) + acetic acid (64-19-7,77671-22-8) → 5-acetamidebenzene-1,3-dicarboxylic acid (6344-50-9)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

DOI:10.1021/acs.inorgchem.1c00767

upstream raw materials:

diethyl 5-aminoisophthalate

acetyl chloride

5-aminoisophthalic acid

5-nitrobenzene-1,3-dicarboxylic acid

Refernces

• 1、 Cabrero-Antonino, Maria,Cao, Chen-chen,Dovgaliuk, Iurii,García, Hermenegildo,Marrot, Jér?me,Martineau-Corcos, Charlotte,Navalón, Sergio,Serre, Christian,Shepard, William,Tissot, Antoine,Wang, Hao,Wang, Sujing,Yu, Liang. "A Robust Titanium Isophthalate Metal-Organic Framework for Visible-Light Photocatalytic CO2 Methanation". . p. 3409 - 3427. Retrieved 2020.
• 2、 Karmakar, Anirban,Rúbio, Guilherme M. D. M.,Guedes Da Silva, M. Fátima C.,Hazra, Susanta,Pombeiro, Armando J. L.. "Solvent-Dependent Structural Variation of Zinc(II) Coordination Polymers and Their Catalytic Activity in the Knoevenagel Condensation Reaction". . p. 4185 - 4197. Retrieved 2015.