Melperone hydrochloride

Base Information

• Chemical Name: Melperone hydrochloride
• CAS No.: 1622-79-3
• Molecular Formula: C₁₆H₂₂FNO*ClH
• Molecular Weight: 299.816
• Hs Code.: 2933399090
• European Community (EC) Number: 216-599-9
• NSC Number: 760102
• UNII: 88G640374K
• DSSTox Substance ID: DTXSID10936649
• Wikidata: Q27269931
• ChEMBL ID: CHEMBL4551527
• Mol file: 1622-79-3.mol

Synonyms:Buronil;Eunerpan;Harmosin;Libernal;Mel-Puren;Melneurin;Melperomerck;melperon;Melperon AbZ;Melperon AL;Melperon AZU;Melperon beta;melperon FG 5111;Melperon Stada;melperon von ct;Melperon-neuraxpharm;Melperon-ratiopharm;Melperon-RPh;Melperon-TEVA;melperone;methylperon;metylperon;metylperon hydrochloride

Chemical Property of Melperone hydrochloride

Chemical Property:

• Vapor Pressure: 6.9E-06mmHg at 25°C
• Melting Point: 209-211℃
• Boiling Point: 376.1°Cat760mmHg
• Flash Point: 181.3°C
• PSA: 20.31000
• Density: g/cm³
• LogP: 4.26040
• Storage Temp.: Desiccate at RT
• Solubility.: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 299.1452202
• Heavy Atom Count: 20
• Complexity: 279

Purity/Quality:

99.3% ^*data from raw suppliers

Melperone Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCN(CC1)CCCC(=O)C2=CC=C(C=C2)F.Cl
• Recent ClinicalTrials: Melperone (an Anti-Psychotic) in Patients With Psychosis Associated With Parkinson's Disease
• Uses: Melperone hydrochloride is a neuroleptic butyrophenone. Melperone is also an antiarrhythmic agent. Melperone is an effective atypical antipsychotic drug used in the treatment of schizophrenia. Melperone Hydrochloride is an atypical antipsychotic drug.
• Therapeutic Function: Neuroleptic

Technology Process of Melperone hydrochloride

There total 1 articles about Melperone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methylpiperidin (626-58-4) + 4-(4-fluorophenyl)-4-oxo-n-butyl chloride (3874-54-2,41167-07-1) → 4-fluoro-γ-(4-methyl-piperidino)-butyrophenone hydrochloride (1622-79-3)

Guidance literature:

With sodium carbonate; sodium iodide; for 4h; Reflux;

upstream raw materials:

4-methylpiperidin

4-(4-fluorophenyl)-4-oxo-n-butyl chloride

Refernces