(Chloromethyl)trimethoxysilane

Base Information

• Chemical Name: (Chloromethyl)trimethoxysilane
• CAS No.: 5926-26-1
• Molecular Formula: C4H11 Cl O3 Si
• Molecular Weight: 170.668
• Hs Code.: 29319090
• European Community (EC) Number: 611-813-0
• DSSTox Substance ID: DTXSID10207987
• Nikkaji Number: J48.145I
• Wikidata: Q72455528
• Mol file: 5926-26-1.mol

Synonyms:(Chloromethyl)trimethoxysilane;5926-26-1;Chloromethyltrimethoxysilane;Silane, (chloromethyl)trimethoxy-;chloromethyl(trimethoxy)silane;SILANE, CHLOROMETHYL-TRIMETHOXY-;Chloromethyl-trimethoxysilane;(Trimethoxychloromethyl)silane;BRN 1071363;EC 611-813-0;MFCD00468107;C4H11ClO3Si;SCHEMBL56275;C4-H11-Cl-O3-Si;DTXSID10207987;Chloromethyltrimethoxysilane, 96%;AMY42183;AKOS006338467;BS-42454;LS-145153;C3073;FT-0690492;D89540;S04420;A832230

Chemical Property of (Chloromethyl)trimethoxysilane

Chemical Property:

• Appearance/Colour: Clear transparent liquid
• Vapor Pressure: 11mmHg at 25°C
• Refractive Index: 1.407 [25°C]
• Boiling Point: 151 °C(lit.)
• Flash Point: 26 °F
• PSA: 27.69000
• Density: 1.132 g/mL at 25 °C(lit.)
• LogP: 1.06080
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 170.0165984
• Heavy Atom Count: 9
• Complexity: 67.9

Purity/Quality:

97% ^*data from raw suppliers

(Chloromethyl)trimethoxysilane >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-29-33

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CO[Si](CCl)(OC)OC
• Uses: Chloromethyltrimethoxysilane may be used in the preparation of 1-methyl-1H-benzimidazole (MBI)-modified nanoparticles.{33} Mesoporous monolithic silica gels can also be prepared from Chloromethyltrimethoxysilane. {34}

Technology Process of (Chloromethyl)trimethoxysilane

There total 9 articles about (Chloromethyl)trimethoxysilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

methanol (67-56-1) + (chloromethyl)trichlorosilane (1558-25-4) → (chloromethyl)trimethoxysilane (5926-26-1)

Guidance literature:

With urea; In diethyl ether; for 4h; Reflux; Inert atmosphere;

DOI:10.1134/S1070363218100092

Reference yield: 85.0%

(chloromethyl)trichlorosilane (1558-25-4) + trimethyl orthoformate (149-73-5) → (chloromethyl)trimethoxysilane (5926-26-1)

Guidance literature:

at 90 ℃; for 5h; Industrial scale;

DOI:10.1134/S1070363216080144

Reference yield:

(chloromethyl)trichlorosilane (1558-25-4) + sodium methylate (124-41-4) → (chloromethyl)trimethoxysilane (5926-26-1)

Guidance literature:

In methanol; at 20 ℃; for 1h; Inert atmosphere;

upstream raw materials:

methanol

(chloromethyl)trichlorosilane

chloromethyl silyl dichloride

trimethyl orthoformate

Downstream raw materials:

phenyl (trimethoxysilyl)methyl selenide

(trimethoxysilyl)methyl-2-methylacrylate

3-(chloromethyl)-1,1,1,5,5,5-hexamethyl-3-[(trimethylsilyl)oxy]trisiloxane

(chloromethyl)(ethyl)diphenylsilane

Refernces

• 1、 -. "Trialkoxysilanes connected with thioether bond on alpha-carbon and containing different functional groups based on sulfydryl-ene click reaction, and preparation". Paragraph 0109-0111. . Retrieved 2019/01/14.
• 2、 Lebedev,Minas’yan,Abramkin,Sheludyakov,Kuzmina,Lebedeva,Surikov,Rybakov. "Synthesis and properties of functionalized alkylalkoxysilanes". . p. 1859 - 1863. Retrieved 2016/10/04.