3-acetyl-2,5-hexanedione

Base Information

• Chemical Name: 3-acetyl-2,5-hexanedione
• CAS No.: 42781-07-7
• Molecular Formula: C8H12 O3
• Molecular Weight: 156.18
• Hs Code.: 2914190090
• Mol file: 42781-07-7.mol

Synonyms:3-Acetyl-2,5-hexanedione

Chemical Property of 3-acetyl-2,5-hexanedione

Chemical Property:

• Vapor Pressure: 0.00438mmHg at 25°C
• Boiling Point: 278°Cat760mmHg
• Flash Point: 114.2°C
• PSA: 51.21000
• Density: 1.025g/cm³
• LogP: 0.75970

Purity/Quality:

99%min ^*data from raw suppliers

3-ACETYL-2,5-HEXANEDIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-acetyl-2,5-hexanedione

There total 4 articles about 3-acetyl-2,5-hexanedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

Okahara's reagent (105104-40-3) + acetylacetone (123-54-6,81235-32-7) → 3-acetylhexane-2,5-dione (42781-07-7)

Guidance literature:

With sodium t-butanolate; at 60 ℃; for 3h;

DOI:10.1021/jo00391a003

Reference yield:

chloroacetone (78-95-5) + nickel(II) acetylacetonate → 3-acetylhexane-2,5-dione (42781-07-7)

Guidance literature:

In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)72244-1

Reference yield:

sodium acetylacetonate (15435-71-9,1118-67-8) + 1-bromoacetone (598-31-2) → 3-acetylhexane-2,5-dione (42781-07-7)

Guidance literature:

With ethanol;

upstream raw materials:

sodium acetylacetonate

chloroacetone

1-bromoacetone

Okahara's reagent

Downstream raw materials:

3-acetyl-2,5-dimethylpyrrole

Refernces