Glycerol 1,3-dipropionate

Base Information

• Chemical Name: Glycerol 1,3-dipropionate
• CAS No.: 18373-31-4
• Molecular Formula: C9H16 O5
• Molecular Weight: 204.223
• Hs Code.: 2915900090
• European Community (EC) Number: 242-250-5
• DSSTox Substance ID: DTXSID20939747
• Nikkaji Number: J25.503C
• Wikidata: Q82916306
• Mol file: 18373-31-4.mol

Synonyms:Glycerol 1,3-dipropionate;18373-31-4;(2-hydroxy-3-propanoyloxypropyl) propanoate;2-hydroxypropane-1,3-diyl dipropanoate;EINECS 242-250-5;SCHEMBL9463770;DTXSID20939747;Glycerin alpha,alpha'-dipropionate;1,2,3-Propanetriol, 1,3-dipropanoate;AM20090076

Chemical Property of Glycerol 1,3-dipropionate

Chemical Property:

• Vapor Pressure: 0.000201mmHg at 25°C
• Refractive Index: n20/D 1.439(lit.)
• Boiling Point: 292°Cat760mmHg
• Flash Point: 107.9°C
• PSA: 72.83000
• Density: 1.122g/cm³
• LogP: 0.25370
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 204.09977361
• Heavy Atom Count: 14
• Complexity: 170

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)OCC(COC(=O)CC)O

Technology Process of Glycerol 1,3-dipropionate

There total 4 articles about Glycerol 1,3-dipropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.3%

propionic acid (802294-64-0,79-09-4) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → glyceryl tripropanoate (139-45-7) + 2,3-dihydroxypropyl propionate (624-47-5) + 2-propionyloxy-propane-1,3-diol (18373-34-7) + 2-hydroxypropane-1,3-diyl dipropionate (18373-31-4) + 2,3-bis-propionyloxy-propan-1-ol (18462-47-0)

Guidance literature:

scandium tris(trifluoromethanesulfonate); In toluene; at 129 ℃;

Reference yield:

propionic acid (802294-64-0,79-09-4) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 2-hydroxypropane-1,3-diyl dipropionate (18373-31-4) + 3-chloro-2-hydroxypropyl propionate (86240-77-9)

Guidance literature:

With graphite oxide; at 50 ℃; for 0.5h; regioselective reaction;

DOI:10.2174/1570178616666190401194252

Reference yield:

propionic acid (802294-64-0,79-09-4) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 2,3-dihydroxypropyl propionate (624-47-5) + 2-hydroxypropane-1,3-diyl dipropionate (18373-31-4)

Guidance literature:

With Ag⁽¹⁺⁾*2H⁽¹⁺⁾*PW₁₂O₄₀^(3-)=AgH₂PW₁₂O₄₀; at 120 ℃; for 0.25h; Autoclave; Green chemistry;

DOI:10.1016/j.jcat.2013.06.026

upstream raw materials:

propionyl chloride

propionic acid

glycerol

epichlorohydrin

Refernces

• 1、 Zhu, Shanhui,Gao, Xiaoqing,Dong, Fang,Zhu, Yulei,Zheng, Hongyan,Li, Yongwang. "Design of a highly active silver-exchanged phosphotungstic acid catalyst for glycerol esterification with acetic acid". . p. 155 - 163. Retrieved 2013/09/02.