Dimethyl 2,5-Dioxahexanedioate

Base Information

• Chemical Name: Dimethyl 2,5-Dioxahexanedioate
• CAS No.: 88754-66-9
• Molecular Formula: C6H10 O6
• Molecular Weight: 178.142
• Hs Code.: 2920909090
• NSC Number: 97193
• DSSTox Substance ID: DTXSID20294585
• Nikkaji Number: J1.387.517K
• Wikidata: Q82033960
• Mol file: 88754-66-9.mol

Synonyms:88754-66-9;2,5-Dioxahexanedioic Acid Dimethyl Ester;Dimethyl 2,5-Dioxahexanedioate;2-methoxycarbonyloxyethyl methyl carbonate;ethane-1,2-diyl dimethyl dicarbonate;2,5-DIOXAHEXANEDIOICACIDDIMETHYLESTER;NSC97193;SCHEMBL47896;DTXSID20294585;MFCD00085447;NSC-97193;AKOS015840251;Ethane-1,2-diyl dimethyl bis(carbonate);BS-44080;CS-0330558;D2455;FT-0610486;ETHYLENE GLYCOL BIS-(METHYL CARBONATE);D90066

Chemical Property of Dimethyl 2,5-Dioxahexanedioate

Chemical Property:

• Refractive Index: 1.4140-1.4170
• Boiling Point: 220 °C
• PSA: 71.06000
• Density: 1,24 g/cm3
• LogP: 0.55240
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 178.04773803
• Heavy Atom Count: 12
• Complexity: 136

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,5-DioxahexanedioicAcidDimethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC(=O)OCCOC(=O)OC

Technology Process of Dimethyl 2,5-Dioxahexanedioate

There total 8 articles about Dimethyl 2,5-Dioxahexanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

ethylene glycol (107-21-1) + carbonic acid dimethyl ester (616-38-6) → 2,5-dioxa-adipic acid dimethyl ester (88754-66-9)

Guidance literature:

With potassium acetate; at 75 ℃; for 0.5h; under 760.051 Torr;

Reference yield:

[1,4,2,3]Dioxadiazinane-2,3-dicarboxylic acid dimethyl ester (91524-12-8) → 2,5-dioxa-adipic acid dimethyl ester (88754-66-9)

Guidance literature:

In various solvent(s); at 137 ℃; for 3h; Yield given; DMSO, 157 deg C, 3 h;

DOI:10.1016/S0040-4039(00)85906-7

Reference yield:

ethylene glycol (107-21-1) + carbonic acid dimethyl ester (616-38-6) → [1,3]-dioxolan-2-one (96-49-1) + 2,5-dioxa-adipic acid dimethyl ester (88754-66-9) + (2-hydroxyethyl) methyl carbonate (106729-72-0)

Guidance literature:

With 1,1,1-trioctyl-1-methylphosphonium methylcarbonate; at 90 ℃; for 4h;

DOI:10.1039/c4ob00655k

upstream raw materials:

methanol

ethylenebis(chloroformate)

ethylene glycol

dimethyl azodicarboxylate

Downstream raw materials:

[1,3]-dioxolan-2-one

carbonic acid dimethyl ester

carbonic acid methyl ester-vinyl ester

methanol

Refernces

• 1、 Eshetu, Gebrekidan Gebresilassie,Grugeon, Sylvie,Kim, Huikyong,Jeong, Sangsik,Wu, Liming,Gachot, Gregory,Laruelle, Stephane,Armand, Michel,Passerini, Stefano. "Comprehensive Insights into the Reactivity of Electrolytes Based on Sodium Ions". . p. 462 - 471. Retrieved 2016/03/09.
• 2、 Dixon, Dabney K. White,Weiss, Randy H.,Nelson, William M.. "THE 1,4,2,3-DIOXADIAZINE RING SYSTEM". . p. 4393 - 4396. Retrieved 2007/10/02.