adenosine 2',3'-cyclic phosphate 5'-phosphate

Base Information

• Chemical Name: adenosine 2',3'-cyclic phosphate 5'-phosphate
• CAS No.: 4527-92-8
• Molecular Formula: C₁₀H₁₃N₅O₉P₂
• Molecular Weight: 409.189
• Mol file: 4527-92-8.mol

Synonyms:Adenosine,cyclic 2',3'-(hydrogen phosphate) 5'-(dihydrogen phosphate) (8CI); Adenosine,cyclic 2',3'-phosphate 5'-phosphate (6CI,7CI);Furo[3,4-d]-1,3,2-dioxaphosphole, 5'-adenylic acid deriv.

Chemical Property of adenosine 2',3'-cyclic phosphate 5'-phosphate

Chemical Property:

• PSA: 220.99000
• LogP: -0.11920

Purity/Quality:

AdenosineCyclic2'',3''-Phosphate5''-Phosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Adenosine Cyclic 2'',3''-Phosphate 5''-Phosphate can be used in biological study for 2'':3''-cyclic PAP, sulfuryl group acceptor in a reaction catalyzed by phenol sulfotransferase. It can also be used in biological study for effect of adenine nucleotides on myo-inositol-1,4,5-trisphosphate-induced calcium release.

Technology Process of adenosine 2',3'-cyclic phosphate 5'-phosphate

There total 5 articles about adenosine 2',3'-cyclic phosphate 5'-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5'-adenosine monophosphate (61-19-8,24937-83-5,67583-85-1) → O2',O3'-hydroxyphosphoryl-O5'-phosphono-adenosine (4527-92-8) + 3'-phosphoadenosine-5'-phosphate (1053-73-2) + adenosine 3',5'-diphosphate (3805-37-6)

Guidance literature:

With sodium hydroxide; Sodium trimetaphosphate; In water; Product distribution; Mechanism; Ambient temperature; reaction time, temperature, and rate of educts;

DOI:10.1246/bcsj.64.490

Reference yield:

pyridine-SO3 complex (42824-16-8) → O2',O3'-hydroxyphosphoryl-O5'-phosphono-adenosine (4527-92-8) + PAPS (482-67-7)

Guidance literature:

With sodium hydrogencarbonate;

Reference yield:

N-chloro-succinimide (128-09-6) + O5'-benzyloxyphosphinoyl-O2',O3'-hydroxyphosphoryl-adenosine → O2',O3'-hydroxyphosphoryl-O5'-phosphono-adenosine (4527-92-8)

Guidance literature:

ueber mehrere Stufen;

upstream raw materials:

N-chloro-succinimide

5'-adenosine monophosphate

pyridine-SO₃ complex

Refernces

• 1、 Tsuhako, Mitsutomo,Kunitomi, Rumi,Baba, Yoshinobu,Miyajima, Tohru. "Phosphorylation of Nucleotides with Inorganic Cyclo-Triphosphate". . p. 490 - 497. Retrieved 2007/10/02.