2H-Pyran, tetrahydro-2-(10-undecynyloxy)-

Base Information

• Chemical Name: 2H-Pyran, tetrahydro-2-(10-undecynyloxy)-
• CAS No.: 51953-88-9
• Deprecated CAS: 151329-50-9
• Molecular Formula: C16H28O2
• Molecular Weight: 252.397
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID70885427
• Nikkaji Number: J422.590B
• Mol file: 51953-88-9.mol

Synonyms:51953-88-9;2H-Pyran, tetrahydro-2-(10-undecynyloxy)-;2H-Pyran, tetrahydro-2-(10-undecyn-1-yloxy)-;2H-Pyran, 2-((10-undecynyl)oxy)tetrahydro-;11-tetrahydropyranyloxyundecyne;SCHEMBL8906511;DTXSID70885427;1-(tetrahydropyran-2-yloxy)undec-10-yne;Tetrahydro-2-(10-undecynyloxy)-2H-pyran

Chemical Property of 2H-Pyran, tetrahydro-2-(10-undecynyloxy)-

Chemical Property:

• Vapor Pressure: 0.000198mmHg at 25°C
• Boiling Point: 338°Cat760mmHg
• Flash Point: 114.6°C
• PSA: 18.46000
• Density: 0.92g/cm³
• LogP: 4.28360
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 10
• Exact Mass: 252.208930132
• Heavy Atom Count: 18
• Complexity: 229

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C#CCCCCCCCCCOC1CCCCO1

Technology Process of 2H-Pyran, tetrahydro-2-(10-undecynyloxy)-

There total 24 articles about 2H-Pyran, tetrahydro-2-(10-undecynyloxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(11,11-dibromo-undec-10-enyloxy)-tetrahydro-pyran (544476-90-6) → 1-[(tetrahydropyran-2-yl)oxy]undec-10-yne (51953-88-9,151329-50-9)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/S0960-894X(02)00999-X

Reference yield: 99.6%

3,4-dihydro-2H-pyran (110-87-2) + undec-10-yn-1-ol (2774-84-7) → 1-[(tetrahydropyran-2-yl)oxy]undec-10-yne (51953-88-9,151329-50-9)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; for 4h; Ambient temperature;

Reference yield: 88.0%

11-(trimethylsilyl)-1-[(tetrahydropyran-2-yl)oxy]undec-10-yne (209474-42-0) → 1-[(tetrahydropyran-2-yl)oxy]undec-10-yne (51953-88-9,151329-50-9)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 48h;

DOI:10.1016/j.chemphyslip.2006.10.003

upstream raw materials:

3,4-dihydro-2H-pyran

undec-10-yn-1-ol

2-(9-bromononyloxy)tetrahydropyran

lithium acetylide-ethylenediamine complex

Downstream raw materials:

Z,Z-3,14-octadecadien-1-ol acetate

Z,Z-4,15-octadecadien-1-ol acetate

Refernces

• 1、 Sun, Dong-Yu,Han, Guan-Ying,Gong, Jing-Xu,Nay, Bastien,Li, Xu-Wen,Guo, Yue-Wei. "Asymmetric Total Synthesis of Distaminolyne A and Revision of Its Absolute Configuration". supporting information. p. 714 - 717. Retrieved 2017/02/10.
• 2、 Carballeira, Nestor M.,Montano, Nashbly,Padilla, Luis F.. "First total syntheses of (Z)-15-methyl-10-hexadecenoic acid and the (Z)-13-methyl-8-tetradecenoic acid". . p. 37 - 44. Retrieved 2007/10/03.