Isonicotinamide, N-(hydroxymethyl)-

Base Information

• Chemical Name: Isonicotinamide, N-(hydroxymethyl)-
• CAS No.: 13538-44-8
• Molecular Formula: C7H8N2O2
• Molecular Weight: 152.1506
• NSC Number: 120640
• UNII: QV15BV5BQ3
• DSSTox Substance ID: DTXSID20159327
• Wikidata: Q83027632
• Mol file: 13538-44-8.mol

Synonyms:ISONICOTINAMIDE, N-(HYDROXYMETHYL)-;N-(Hydroxymethyl)isonicotinamide;13538-44-8;NSC 120640;BRN 0129518;N-(hydroxymethyl)pyridine-4-carboxamide;QV15BV5BQ3;4-Pyridinecarboxamide, N-(hydroxymethyl)-;NSC-120640;4-22-00-00534 (Beilstein Handbook Reference);NSC120640;UNII-QV15BV5BQ3;N-hydroxymethylisonicotinamide;SCHEMBL7273110;DTXSID20159327;AKOS002685606;LS-84810;N-(HYDROXYMETHYL)-4-PYRIDINECARBOXAMIDE

Chemical Property of Isonicotinamide, N-(hydroxymethyl)-

Chemical Property:

• Vapor Pressure: 4.46E-08mmHg at 25°C
• Boiling Point: 427.7°Cat760mmHg
• Flash Point: 212.5°C
• Density: 1.262g/cm³
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 152.058577502
• Heavy Atom Count: 11
• Complexity: 132

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=CC=C1C(=O)NCO

Technology Process of Isonicotinamide, N-(hydroxymethyl)-

There total 2 articles about Isonicotinamide, N-(hydroxymethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + isonicotinamide (1453-82-3) → N-Hydroxymethyl-isonicotinsaeureamid (13538-44-8)

Guidance literature:

With water;

Reference yield:

→ N-Hydroxymethyl-isonicotinsaeureamid (13538-44-8)

Guidance literature:

Isonicotinsaeureamid, Paraformaldehyd, NaOH (160-165grad);

upstream raw materials:

formaldehyd

isonicotinamide