10,11-Dihydro-5H-dibenzo[a,d]cycloheptene

Base Information

• Chemical Name: 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene
• CAS No.: 833-48-7
• Molecular Formula: C15H14
• Molecular Weight: 194.276
• Hs Code.: 2902909090
• European Community (EC) Number: 212-630-5
• NSC Number: 86156
• UNII: GU7KLN5ED5
• DSSTox Substance ID: DTXSID10232254
• Nikkaji Number: J195.102E
• Wikipedia: Dibenzocycloheptene
• Wikidata: Q256369
• ChEMBL ID: CHEMBL564180
• Mol file: 833-48-7.mol

Synonyms:dibenzocycloheptadiene

Chemical Property of 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene

Chemical Property:

• Vapor Pressure: 5.89E-05mmHg at 25°C
• Melting Point: 74-76 °C(lit.)
• Refractive Index: 1.5000 (estimate)
• Boiling Point: 160-165 °C2 mm Hg(lit.)
• Flash Point: 135.1°C
• PSA: 0.00000
• Density: 1.056g/cm³
• LogP: 3.37600
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 194.109550447
• Heavy Atom Count: 15
• Complexity: 186

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dibenzosuberane 98% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Aromatic Hydrocarbons
• Canonical SMILES: C1CC2=CC=CC=C2CC3=CC=CC=C31
• Uses: 10,11-DIHYDRO-5 H-DIBENZO[A,D]CYCLOHEPTENE is used as the base structure of various tricyclic antidepressants. Studies suggest that Dibenzosuberane and its analogues may have anti-viral properties.

Technology Process of 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene

There total 53 articles about 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

[2-(2-phenylethyl)phenyl]methanol (835-78-9) → dibenzosuberane (833-48-7)

Guidance literature:

With Nafion-H; In hexane; for 1h; Heating;

Reference yield: 100.0%

dibenzosuberenon (2222-33-5) → dibenzosuberane (833-48-7)

Guidance literature:

With iodine; hypophosphorous acid; In acetic acid; for 72h; Heating;

DOI:10.1016/S0040-4039(00)01359-9

Reference yield: 98.0%

10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one (1210-35-1) → dibenzosuberane (833-48-7)

Guidance literature:

With iodine; hypophosphorous acid; In acetic acid; for 24h; Heating;

DOI:10.1016/S0040-4039(00)01359-9

upstream raw materials:

suberene

o-phenethylbenzoic acid

dibenzosuberenon

10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one

Downstream raw materials:

10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one

dibenzosuberenon

2-(10,11-dihydro-5H-benzo[a,d]cyclohepten-5-yl)-1,3-diphenylpropane-1,3-dione

2-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1-phenylethan-1-one

Refernces

• 1、 Tashiro,M.,Yamato,T.. "-". . p. 214 - 215. Retrieved 1978.
• 2、 Mendez-Vega, Enrique,Maehara, Mika,Raut, Akshay Hemant,Mieres-Perez, Joel,Tsuge, Masashi,Lee, Yuan-Pern,Sander, Wolfram. "Activation of Molecular Hydrogen by Arylcarbenes". . p. 18801 - 18808. Retrieved 2018/11/27.
• 3、 Mahdi, Tayseer,Stephan, Douglas W.. "Facile Protocol for Catalytic Frustrated Lewis Pair Hydrogenation and Reductive Deoxygenation of Ketones and Aldehydes". . p. 8511 - 8514. Retrieved 2015/11/27.