2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE

Base Information

• Chemical Name: 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE
• CAS No.: 4746-67-2
• Molecular Formula: C7H8 N2
• Molecular Weight: 120.154
• Hs Code.: 2933990090
• Mol file: 4746-67-2.mol

Synonyms:Benzimidazoline(8CI)

Chemical Property of 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE

Chemical Property:

• Boiling Point: 266.3±20.0 °C(Predicted)
• PKA: 6.93±0.20(Predicted)
• PSA: 24.06000
• Density: 1.086±0.06 g/cm3(Predicted)
• LogP: 1.75750
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98% ^*data from raw suppliers

2,3-Dihydro-1H-benzo[d]imidazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE

There total 5 articles about 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

benzimidazole hydrochloride (18227-18-4) → benzimidazoline (4746-67-2)

Guidance literature:

With lithium triethylborohydride; In tetrahydrofuran; at -78 - 20 ℃; for 3h; Schlenk technique;

DOI:10.1016/j.poly.2017.08.045

Reference yield:

2,3-dihydrobenzimidazol-2-thione (583-39-1,2080-59-3) → benzimidazoline (4746-67-2)

Guidance literature:

With sodium tetrahydroborate; nickel dichloride; In methanol; at 0 ℃; for 1h;

DOI:10.1002/cmdc.201000275

Reference yield:

N-methylene1,2-phenylenediamine (1355363-17-5) → benzimidazoline (4746-67-2)

Guidance literature:

With cerium(III) chloride; sodium iodide; at 100 ℃; Green chemistry;

DOI:10.3184/174751913X13575704209748

upstream raw materials:

2,3-dihydrobenzimidazol-2-thione

1,2-diamino-benzene

N-methylene1,2-phenylenediamine

benzimidazole hydrochloride

Downstream raw materials:

1-acetylbenzimidazole

benzoimidazole

Refernces

• 1、 Zhu, Xun,Wei, Yunyang. "An efficient and environmental benign synthesis of 2-benzimidazoles and 2-benzothiazoles using CeCl3-NaI as catalyst". . p. 119 - 121. Retrieved 2013/04/23.