Technology Process of Dibenz[b,f]oxepin
There total 7 articles about Dibenz[b,f]oxepin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; DavePhos;
In
toluene;
at 180 ℃;
for 0.5h;
Inert atmosphere;
Microwave irradiation;
DOI:10.1055/s-0031-1290317
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / Reflux
2.1: potassium tert-butylate / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; DavePhos / toluene / 0.5 h / 180 °C / Inert atmosphere; Microwave irradiation
With
tris-(dibenzylideneacetone)dipalladium(0); potassium tert-butylate; potassium carbonate; sodium t-butanolate; DavePhos;
In
tetrahydrofuran; N,N-dimethyl-formamide; toluene;
2.2: Wittig reaction / 3.1: Mizoroki-Heck cyclization;
DOI:10.1055/s-0031-1290317
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / Reflux
2.1: potassium tert-butylate / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; DavePhos / toluene / 0.5 h / 180 °C / Inert atmosphere; Microwave irradiation
With
tris-(dibenzylideneacetone)dipalladium(0); potassium tert-butylate; potassium carbonate; sodium t-butanolate; DavePhos;
In
tetrahydrofuran; N,N-dimethyl-formamide; toluene;
2.2: Wittig reaction / 3.1: Mizoroki-Heck cyclization;
DOI:10.1055/s-0031-1290317
