2-ethoxy-3,4-dimethyl-2-phenylmorpholine hydrochloride (1:1)

Base Information

• Chemical Name: 2-ethoxy-3,4-dimethyl-2-phenylmorpholine hydrochloride (1:1)
• CAS No.: 124497-83-2
• Molecular Formula: C₁₄H₂₁NO₂*ClH
• Molecular Weight: 271.787
• Mol file: 124497-83-2.mol

Synonyms:Morpholine,2-ethoxy-3,4-dimethyl-2-phenyl-, hydrochloride (9CI)

Chemical Property of 2-ethoxy-3,4-dimethyl-2-phenylmorpholine hydrochloride (1:1)

Chemical Property:

• Vapor Pressure: 0.000426mmHg at 25°C
• Boiling Point: 315.9°Cat760mmHg
• Flash Point: 101.2°C
• Density: g/cm³

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ethoxy-3,4-dimethyl-2-phenylmorpholine hydrochloride (1:1)

There total 2 articles about 2-ethoxy-3,4-dimethyl-2-phenylmorpholine hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

ethanol (64-17-5) + 3,4-Dimethyl-2-phenyl-morpholin-2-ol; hydrochloride (124497-75-2) → 2-Ethoxy-3,4-dimethyl-2-phenyl-morpholine; hydrochloride (124497-83-2)

Guidance literature:

With acid;

DOI:10.1016/0223-5234(89)90112-8

Reference yield:

2-bromo-1-phenyl-1-propanone (2114-00-3) → 2-Ethoxy-3,4-dimethyl-2-phenyl-morpholine; hydrochloride (124497-83-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / 2.) ethereal hydrogen chloride / diethyl ether / Ambient temperature

2: 89 percent / acid

With hydrogenchloride; In diethyl ether;

DOI:10.1016/0223-5234(89)90112-8

upstream raw materials:

ethanol

3,4-Dimethyl-2-phenyl-morpholin-2-ol; hydrochloride

2-bromo-1-phenyl-1-propanone

Refernces