Benzaldehyde, 2-methyl-, (2,4-dinitrophenyl)hydrazone

Base Information

• Chemical Name: Benzaldehyde, 2-methyl-, (2,4-dinitrophenyl)hydrazone
• CAS No.: 1773-44-0
• Molecular Formula: C14H12 N4 O4
• Molecular Weight: 300.274
• Hs Code.: 2928000090
• European Community (EC) Number: 623-763-7
• NSC Number: 409528
• Nikkaji Number: J3.471.254I
• Mol file: 1773-44-0.mol

Synonyms:1773-44-0;o-Tolualdehyde-2,4-DNPH;o-Tolualdehyde 2,4-dinitrophenylhydrazone;o-Tolualdehyde, (2,4-dinitrophenyl)hydrazone;Benzaldehyde, 2-methyl-, 2-(2,4-dinitrophenyl)hydrazone;Benzaldehyde, 2-methyl-, (2,4-dinitrophenyl)hydrazone;2'-Methylbenzaldehyde 2,4-Dinitrophenylhydrazone;MFCD00191584;NSC409528;(E)-1-(2,4-dinitrophenyl)-2-(2-methylbenzylidene)hydrazine;QUIFNJPMGQCNMH-OQLLNIDSSA-N;BAA77344;AKOS001002054;NSC-409528;o-Tolualdehyde,4-dinitrophenyl)hydrazone;o-Tolualdehyde 2,4-dinitro-phenylhydrazone;CS-0448712;o-Tolualdehyde-2,4-DNPH, analytical standard;2-Methylbenzaldehyde (2,4-dinitrophenyl)hydrazone #;2-Methylbenzaldehyde (Z)-(2,4-dinitrophenyl)hydrazone;1-(2,4-dinitrophenyl)-2-(2-methylbenzylidene)hydrazine;Benzaldehyde,2-methyl-,2-(2,4-dinitrophenyl)hydrazone;N-[(2-methylphenyl)methylideneamino]-2,4-dinitro-aniline

Chemical Property of Benzaldehyde, 2-methyl-, (2,4-dinitrophenyl)hydrazone

Chemical Property:

• Vapor Pressure: 4.7E-09mmHg at 25°C
• Melting Point: 195-198 °C(lit.)
• Boiling Point: 471.3 °C at 760 mmHg
• PKA: 11.23±0.10(Predicted)
• Flash Point: 238.9 °C
• PSA: 116.03000
• Density: 1.36 g/cm³
• LogP: 4.37680
• Storage Temp.: 2-8°C
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 300.08585488
• Heavy Atom Count: 22
• Complexity: 432

Purity/Quality:

98%,99%, ^*data from raw suppliers

o-Tolualdehyde 2,4-Dinitrophenylhydrazone >98.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,T,F,Xn
• Statements: 36/37/38-23/24/25-11-41-37/38-36-20/21/22-22
• Safety Statements: 26-36-45-27-16-39-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC=CC=C1C=NNC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]
• Isomeric SMILES: CC1=CC=CC=C1/C=N/NC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]

Technology Process of Benzaldehyde, 2-methyl-, (2,4-dinitrophenyl)hydrazone

There total 4 articles about Benzaldehyde, 2-methyl-, (2,4-dinitrophenyl)hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-methylphenyl aldehyde (529-20-4) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → o-tolualdehyde (2,4-dinitrophenyl)hydrazone (1773-44-0)

Guidance literature:

With acetic acid; In methanol; Reflux;

Reference yield:

ortho-methylbenzoic acid (118-90-1) → o-tolualdehyde (2,4-dinitrophenyl)hydrazone (1773-44-0)

Guidance literature:

Multi-step reaction with 3 steps

1: phosphorus (III)-chloride / 120 °C

2: PCl₅; toluene / 100 °C / Behandeln des Reaktionsprodukts mit SnCl₂ und HCl in Aether und anschliessendes Erhitzen mit Wasser unter Durchleiten von Wasserdampf

With phosphorus pentachloride; toluene; phosphorus trichloride;

DOI:10.1039/jr9360000352

Reference yield:

2-methyl-N-phenylbenzamide (7055-03-0) → o-tolualdehyde (2,4-dinitrophenyl)hydrazone (1773-44-0)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₅; toluene / 100 °C / Behandeln des Reaktionsprodukts mit SnCl₂ und HCl in Aether und anschliessendes Erhitzen mit Wasser unter Durchleiten von Wasserdampf

With phosphorus pentachloride; toluene;

DOI:10.1039/jr9360000352

upstream raw materials:

2-methylphenyl aldehyde

(2,4-dinitro-phenyl)-hydrazine

ortho-methylbenzoic acid

2-methyl-N-phenylbenzamide

Downstream raw materials:

2-methylphenyl aldehyde

Refernces

• 1、 Ahad, Ghulam,Khan, Momin,Khan, Asif,Ibrahim, Mohammad,Salar, Uzma,Kanwal,Khan, Khalid Mohammed,Perveen, Shahnaz. "Synthesis, structural characterization, and antioxidant activities of 2,4-dinitrophenyl-hydrazone derivatives". . p. 961 - 973. Retrieved 2018/10/02.
• 2、 Banerji, Kalyan K.. "Kinetics and Mechanism of the Oxidation of Substituted Benzylamines by N-Chlorosuccinimide". . p. 1015 - 1020. Retrieved 2007/10/02.