2-hydroxyheptanal

Base Information

• Chemical Name: 2-hydroxyheptanal
• CAS No.: 17046-02-5
• Molecular Formula: C7H14 O2
• Molecular Weight: 130.187
• Mol file: 17046-02-5.mol

Synonyms:2-Hydroxyheptaldehyde;2-Hydroxyheptanal

Chemical Property of 2-hydroxyheptanal

Chemical Property:

• Vapor Pressure: 0.194mmHg at 25°C
• Boiling Point: 185.7°Cat760mmHg
• Flash Point: 70.9°C
• PSA: 37.30000
• Density: 0.934g/cm³
• LogP: 1.12650

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-hydroxyheptanal

There total 19 articles about 2-hydroxyheptanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2-Chloromethanesulfonyl-3-pentyl-oxirane (103722-09-4) → 2-hydroxyheptanal dimer (17046-02-5)

Guidance literature:

With titanium tetrachloride; In dichloromethane; for 1h;

Reference yield: 40.0%

1,2-epoxyheptane (5063-65-0) → 2-hydroxyheptanal dimer (17046-02-5) + 1-hydroxypentan-2-one (17046-01-4)

Guidance literature:

With bis-[(trifluoroacetoxy)iodo]benzene; In dichloromethane; for 24h; Product distribution; Ambient temperature; other oxiranes;

DOI:10.1021/jo00338a041

Reference yield:

2-bromoheptanal (16486-84-3) + water (7732-18-5) → 2-hydroxyheptanal dimer (17046-02-5) + oenanthic acid (111-14-8) + 1-hydroxypentan-2-one (17046-01-4) + 3-hydroxy-2-heptanone (68113-60-0)

Guidance literature:

Produkt₅: 2-Hydroxy-heptan-3-on;

DOI:10.1021/ja01639a029

upstream raw materials:

2-bromo-1,1-diethoxy-heptane

2-chloro-heptanal

2-oxoheptyl acetate

1,2-epoxyheptane

Downstream raw materials:

3-hydroxy-2-heptanone

Refernces

• 1、 Cannillo, Alexandre,Norsikian, Stephanie,Retailleau, Pascal,Dau, Marie-Elise Tran Huu,Iorga, Bogdan I.,Beau, Jean-Marie. "Fast synthesis of complex enantiopure heterocyclic scaffolds by a tandem sequence of simple transformations on α-hydroxyaldehydes". . p. 9127 - 9131. Retrieved 2013/07/26.
• 2、 Kern, Werner,Spiteller, Gerhard. "Synthesis and properties of natural occurring α-hydroxyaldehydes". . p. 4347 - 4362. Retrieved 2007/10/03.