Diethylaminoethanol hydrochloride

Base Information

• Chemical Name: Diethylaminoethanol hydrochloride
• CAS No.: 14426-20-1
• Molecular Formula: C6H15 N O . Cl H
• Molecular Weight: 153.652
• Hs Code.: 2921199090
• Mol file: 14426-20-1.mol

Synonyms:BETA-(DIETHYLAMINO)ETHYL ALCOHOL HYDROCHLORIDE;4620-71-7;DiEthylEthanolAmmonium Chloride;AKOS015898996

Chemical Property of Diethylaminoethanol hydrochloride

Chemical Property:

• Melting Point: 133°C
• Boiling Point: 478.8°Cat760mmHg
• Flash Point: 243.4°C
• PSA: 23.47000
• Density: 1.52g/cm³
• LogP: 1.12250
• Storage Temp.: Refrigerator
• Sensitive.: Moisture Sensitive
• Solubility.: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 153.0920418
• Heavy Atom Count: 9
• Complexity: 43.8

Purity/Quality:

98% or more ^*data from raw suppliers

2-DiethylaminoethanolHydrochloride ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC[NH+](CC)CCO.[Cl-]
• Uses: 2-Diethylaminoethanol Hydrochloride (cas# 14426-20-1) is a compound useful in organic synthesis.

Technology Process of Diethylaminoethanol hydrochloride

There total 2 articles about Diethylaminoethanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cyclodrinhydrochlorid (78853-39-1) → phenylacetic acid (103-82-2) + α-(1-Hydroxycyclopentyl)phenylessigsaeure (25209-52-3) + N,N-diethylethanolammonium chloride (14426-20-1)

Guidance literature:

at 120 ℃; Mechanism; degradation also in aq. solution and with aq. HCl and aq. KOH (6 h, reflux);

Reference yield:

2-(Diethylamino)ethanol (100-37-8) → N,N-diethylethanolammonium chloride (14426-20-1)

Guidance literature:

With hydrogenchloride; In dichloromethane; water; at 20 ℃; for 2h;

DOI:10.1016/j.molcata.2010.05.010

Reference yield: 48.4%

2,5-dibromohydroquinone (14753-51-6) + N,N-diethylethanolammonium chloride (14426-20-1) → 2,5-bis[3-(N,N-diethylamino)-1-oxapropyl]-1,4-dibromobenzene (233753-19-0)

Guidance literature:

With potassium carbonate; In acetone; for 72h; Heating;

DOI:10.1021/ma010974r

upstream raw materials:

Cyclodrinhydrochlorid

2-(Diethylamino)ethanol

Downstream raw materials:

2-hydroxy-4-nitro-benzoic acid-(2-diethylamino-ethyl ester)

4-amino-2-fluoro-benzoic acid-(2-diethylamino-ethyl ester); hydrochloride

chloroprocaine hydrochloride

3,4,5-tripropoxy-benzoic acid-(2-diethylamino-ethyl ester)

Refernces

• 1、 Martin, Elisabeth,Pohloudek-Fabini, R.. "Contribution to the Stability of Cyclodrin Hydrochloride. Part 1: The Mechanism of Degradation of Cyclodrin Hydrochloride and the Detection of Its Degradation Products in the Presence of the Intact Active Agent". . p. 480 - 482. Retrieved 2007/10/02.