1,2,3-TRIPHENYL-1-INDENOL

Base Information

• Chemical Name: 1,2,3-TRIPHENYL-1-INDENOL
• CAS No.: 42454-94-4
• Molecular Formula: C27H20O
• Molecular Weight: 360.455
• Hs Code.: 2906299090
• Mol file: 42454-94-4.mol

Synonyms:1,2,3-triphenyl-1H-inden-1-ol;1,2,3-Triphenyl-1-Indenol;1,2,3-Triphenylindenol-(1);3-Oxy-1.2.3-triphenyl-inden;1-Hydroxy-1,2,3-triphenyl-inden;3-oxy-1.2.3-triphenyl-indene;Inden-1-ol,1,2,3-triphenyl;

Chemical Property of 1,2,3-TRIPHENYL-1-INDENOL

Chemical Property:

• Vapor Pressure: 5.39E-11mmHg at 25°C
• Boiling Point: 504.4°Cat760mmHg
• Flash Point: 204.4°C
• PSA: 20.23000
• Density: 1.218g/cm³
• LogP: 5.89520

Purity/Quality:

99% ^*data from raw suppliers

1,2,3-TRIPHENYL-1-INDENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,3-TRIPHENYL-1-INDENOL

There total 10 articles about 1,2,3-TRIPHENYL-1-INDENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

benzophenone (119-61-9) + diphenyl acetylene (501-65-5) → 1,2,3-triphenyl-1H-inden-1-ol (42454-94-4)

Guidance literature:

With [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; sodium acetate; 1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene; In tetrahydrofuran; at 20 - 60 ℃; for 48h; regioselective reaction;

DOI:10.1002/anie.201209031

Reference yield: 85.0%

diphenyl acetylene (501-65-5) → 1,2,3-triphenyl-1H-inden-1-ol (42454-94-4)

Guidance literature:

In benzene; for 18h; Heating;

DOI:10.1016/j.jorganchem.2005.04.050

Reference yield: 75.0%

o-bromobenzophenone (13047-06-8) + diphenyl acetylene (501-65-5) → 1,2,3-triphenyl-1H-inden-1-ol (42454-94-4)

Guidance literature:

With palladium diacetate; potassium acetate; triphenylphosphine; In N,N-dimethyl-formamide; at 120 ℃; for 24h;

DOI:10.1021/ja983645w

upstream raw materials:

1-bromo-1,2,3-triphenyl-indene

sodium acetate

acetic acid

2,3-diphenyl-1H-inden-1-one

Downstream raw materials:

methyl-(1,2,3-triphenyl-inden-1-yl)-ether

2,2,3-triphenyl-indan-1-one

1,2,3-triphenylindan

ethyl-(1,2,3-triphenyl-inden-1-yl)-ether

Refernces

• 1、 Zhang, Jing,Ugrinov, Angel,Zhao, Pinjing. "Ruthenium(II)/N-heterocyclic carbene catalyzed [3+2] carbocyclization with aromatic N-H ketimines and internal alkynes". supporting information. p. 6681 - 6684. Retrieved 2013/07/26.
• 2、 Muralirajan, Krishnamoorthy,Parthasarathy, Kanniyappan,Cheng, Chien-Hong. "Regioselective synthesis of indenols by rhodium-catalyzed C-H activation and carbocyclization of aryl ketones and alkynes". supporting information; experimental part. p. 4169 - 4172. Retrieved 2011/06/24.