N-(2-methoxyethyl)urea

Base Information

• Chemical Name: N-(2-methoxyethyl)urea
• CAS No.: 22033-10-9
• Molecular Formula: C4H10 N2 O2
• Molecular Weight: 118.136
• European Community (EC) Number: 842-740-4
• DSSTox Substance ID: DTXSID70176504
• Nikkaji Number: J1.932.981J
• Wikidata: Q83046827
• Mol file: 22033-10-9.mol

Synonyms:N-(2-methoxyethyl)urea;22033-10-9;1-(2-methoxyethyl)urea;2-methoxyethylurea;(2-methoxyethyl)urea;Urea, (2-methoxyethyl)-;(2-methoxy-ethyl)-urea;2-Methoxyethyl carbamide;SCHEMBL219555;DTXSID70176504;MFCD03425768;AKOS000117078;CS-0213036;FT-0680383;EN300-06417;4R-0241;J-503039;Z56904572

Chemical Property of N-(2-methoxyethyl)urea

Chemical Property:

• Vapor Pressure: 0.434mmHg at 25°C
• Melting Point: 73-75°C
• Boiling Point: 194.8°Cat760mmHg
• Flash Point: 71.6°C
• PSA: 64.35000
• Density: 1.068g/cm³
• LogP: 0.39230
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 118.074227566
• Heavy Atom Count: 8
• Complexity: 74.4

Purity/Quality:

98%min ^*data from raw suppliers

N-(2-Methoxyethyl)urea ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCCNC(=O)N

Technology Process of N-(2-methoxyethyl)urea

There total 4 articles about N-(2-methoxyethyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

potassium cyanide (151-50-8) + (2-methoxyethyl)amine hydrochloride (18600-40-3) → 1-(2-methoxyethyl)urea (22033-10-9)

Guidance literature:

With water; for 4h; Heating;

DOI:10.1021/jm980693i

Reference yield:

potassium cyanate (590-28-3) + 2-methoxyethylamine (109-85-3) → 1-(2-methoxyethyl)urea (22033-10-9)

Guidance literature:

In water; at 100 ℃; for 3h;

Reference yield:

2-methoxyethylamine (109-85-3) → 1-(2-methoxyethyl)urea (22033-10-9)

Guidance literature:

In water;

upstream raw materials:

potassium cyanide

(2-methoxyethyl)amine hydrochloride

potassium cyanate

2-methoxyethylamine

Downstream raw materials:

6-amino-1-(2-methoxyethyl)-1,3-dihydropyrimidine-2,4-dione

Refernces

• 1、 -. "Inhibitors of Herpes Simplex virus uracil-DNA glycosylase". . . Retrieved 2008/06/13.