Dextrallorphan

Base Information

• Chemical Name: Dextrallorphan
• CAS No.: 5822-43-5
• Molecular Formula: C19H25 N O
• Molecular Weight: 283.414
• Wikipedia: Dextrallorphan
• ChEMBL ID: CHEMBL1254683
• Mol file: 5822-43-5.mol

Synonyms:dextrallorphan;dextrallorphan hydrobromide, (9alpha,13alpha,14alpha)-isomer;dextrallorphan hydrochloride;dextrallorphan, (+-)-isomer

Chemical Property of Dextrallorphan

Chemical Property:

• Vapor Pressure: 4.02E-08mmHg at 25°C
• Boiling Point: 433.5°Cat760mmHg
• Flash Point: 214.2°C
• PSA: 23.47000
• Density: 1.14g/cm³
• LogP: 3.57450
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 283.193614421
• Heavy Atom Count: 21
• Complexity: 408

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCN1CCC23CCCCC2C1CC4=C3C=C(C=C4)O
• Isomeric SMILES: C=CCN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)O

Technology Process of Dextrallorphan

There total 4 articles about Dextrallorphan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

allyl bromide (106-95-6) → Dextrallorphan (5822-43-5)

Guidance literature:

With chloroform;

DOI:10.1002/hlca.19510340715

Reference yield:

4-((S)-2-allyl-1,2,3,4,5,6,7,8-octahydro-[1]isoquinolylmethyl)-phenol → Dextrallorphan (5822-43-5)

Guidance literature:

With phosphoric acid; Erhitzen des Reaktionsgemisches mit wss.Salzsaeure;

Reference yield:

→ C19H25NO (152-02-3,5822-43-5,64783-66-0,64970-77-0)

Guidance literature:

Amin (IX), Allylbromid;

upstream raw materials:

allyl bromide