Carboprost

Base Information

• Chemical Name: Carboprost
• CAS No.: 59286-19-0
• Molecular Formula: C21H36O5
• Molecular Weight: 368.5075
• UNII: 7B5032XT6O
• ChEMBL ID: CHEMBL1237122
• DSSTox Substance ID: DTXSID4022739
• Metabolomics Workbench ID: 2441
• NCI Thesaurus Code: C61662
• Nikkaji Number: J17.442D
• Pharos Ligand ID: DPSJ5FBD5ZYB
• RXCUI: 2051
• Wikidata: Q5038067
• Wikipedia: Carboprost
• Mol file: 59286-19-0.mol

Synonyms:15 Methylprostaglandin F2alpha;15(S)-15-Methyl PGF2alpha;15-Methylprostaglandin F2alpha;Carboprost

Chemical Property of Carboprost

Chemical Property:

• Boiling Point: 536.6°Cat760mmHg
• Flash Point: 292.4°C
• Density: 1.139g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 12
• Exact Mass: 368.25627424
• Heavy Atom Count: 26
• Complexity: 473

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCC(C)(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O
• Isomeric SMILES: CCCCC[C@@](C)(/C=C/[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)O)O)O
• Recent ClinicalTrials: Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial

Technology Process of Carboprost

There total 2 articles about Carboprost which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (Z)-7-[(1R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hydroxy-3-methyl-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid (35700-23-3,35700-24-4,35700-25-5,35864-81-4,41691-84-3,59286-19-0,62446-63-3,62776-95-8,68906-67-2,68906-68-3,76498-29-8,80124-57-8,90695-58-2,90695-59-3,100019-29-2,113626-85-0)

Guidance literature:

15-Oxo-1,9,11-tris-OSi(Me)3-PGF(2α), 1.) MeMgBr, 2.) W.;

Reference yield:

→ (Z)-7-[(1R,3R)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-3-methyl-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid (35700-23-3,35700-24-4,35700-25-5,35864-81-4,41691-84-3,59286-19-0,62446-63-3,62776-95-8,68906-67-2,68906-68-3,76498-29-8,80124-57-8,90695-58-2,90695-59-3,100019-29-2,113626-85-0)

Guidance literature:

TMS-Derivat v. 15-Oxo-PGF(2β) u. CH3MgBr;