Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-

Base Information

• Chemical Name: Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-
• CAS No.: 15456-86-7
• Molecular Formula: C4H3BrN2O2
• Molecular Weight: 190.984
• Hs Code.: 2933990090
• Mol file: 15456-86-7.mol

Synonyms:3,6-Pyridazinedione,4-bromo-1,2-dihydro- (7CI,8CI,9CI);4-Bromo-1,2-dihydropyridazine-3,6-dione;NSC 79701;4-Bromo-pyridazine-3,6-diol;Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-;

Chemical Property of Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-

Chemical Property:

• Refractive Index: 1.59
• PKA: 7?+-.0.40(Predicted)
• PSA: 65.98000
• Density: 1.965 g/cm³
• LogP: 0.23800
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Bromo-1,2-dihydropyridazine-3,6-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro-

There total 3 articles about Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

bromomaleic anhydride (5926-51-2) → 4-bromo-1,2-dihydropyridazine-3,6-dione (15456-86-7,43068-41-3)

Guidance literature:

With hydrazinium sulfate; In water; at 100 ℃; for 12h;

DOI:10.1021/jo501930s

Reference yield:

bromomaleic anhydride (5926-51-2) + hydrazinium sulfate (10034-93-2) → 4-bromo-1,2-dihydropyridazine-3,6-dione (15456-86-7,43068-41-3)

Guidance literature:

In water;

Reference yield:

→ 4-bromo-1,2-dihydropyridazine-3,6-dione (15456-86-7,43068-41-3)

Guidance literature:

Brommaleinsaeureanhydrid;

upstream raw materials:

bromomaleic anhydride

hydrazinium sulfate

Downstream raw materials:

4-bromo-2-{[4-(methyloxy)phenyl]methyl}-6-({[4-(methyloxy)phenyl]methyl}oxy)-3(2H)-pyridazinone

5-bromo-2-{[4-(methyloxy)phenyl]methyl}-6-({[4-(methyloxy)phenyl]methyl}oxy)-3(2H)-pyridazinone

3,4,6-trichloropyridazine

3,6-dichloro-4-(pyridin-4-yl)pyridazine

Refernces

• 1、 -. "THYROID HORMONE RECEPTOR AGONISTS AND USES THEREOF". Paragraph 00333; 00382. . Retrieved 2020/01/08.
• 2、 Arghiani, Zahra,Seyedi, Seyed Mohammad,Bakavoli, Mehdi,Nikpour, Mohsen. "Synthesis of new derivatives of 10H-benzo[b]pyridazino[3,4-e][1,4]thiazines". . p. 215 - 218. Retrieved 2015/08/24.