sodium 3-amino-4-chlorobenzenesulphonate

Base Information

• Chemical Name: sodium 3-amino-4-chlorobenzenesulphonate
• CAS No.: 59312-69-5
• Molecular Formula: C6H6 Cl N O3 S . Na
• Molecular Weight: 229.619
• Mol file: 59312-69-5.mol

Synonyms:Benzenesulfonicacid, 3-amino-4-chloro-, monosodium salt (9CI); Metanilic acid, 4-chloro-, sodiumsalt (6CI)

Chemical Property of sodium 3-amino-4-chlorobenzenesulphonate

Chemical Property:

• PSA: 91.60000
• LogP: 2.48830

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sodium 3-amino-4-chlorobenzenesulphonate

There total 1 articles about sodium 3-amino-4-chlorobenzenesulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-3-nitrobenzenesulphonic acid sodium salt (17691-19-9) → sodium 4-chloro-3-aminobenzensulfonate (59312-69-5)

Guidance literature:

With hydrogen; In methanol; water; at 20 ℃;

Reference yield:

sodium 4-chloro-3-aminobenzensulfonate (59312-69-5) + Boc-Glu-OtBu hydrochloride? (1220450-42-9) → C20H29ClN2O8S

Guidance literature:

With 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

sodium 4-chloro-3-aminobenzensulfonate (59312-69-5) → N5-(2-chloro-5-sulfophenyl)-L-glutamine (1220125-31-4)

Guidance literature:

Multi-step reaction with 2 steps

1: HATU; N-ethyl-N,N-diisopropylamine; 1-hydroxy-7-aza-benzotriazole / N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / 2 h / 20 °C

With 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; In N,N-dimethyl-formamide;

upstream raw materials:

4-chloro-3-nitrobenzenesulphonic acid sodium salt

Downstream raw materials:

N⁵-(2-chloro-5-sulfophenyl)-L-glutamine

Refernces

• 1、 -. "CASR AGONIST". Page/Page column 24. . Retrieved 2011/08/04.