2-methylnorharman

Base Information

• Chemical Name: 2-methylnorharman
• CAS No.: 5667-11-8
• Molecular Formula: C12H11 N2 . I
• Molecular Weight: 310.137
• Mol file: 5667-11-8.mol

Synonyms:2-Methyl-9H-pyrido[3,4-b]indoliumiodide (6CI,7CI); 9H-Pyrido[3,4-b]indolium, 2-methyl-, iodide (8CI,9CI); 1-DemethylmelinonineF iodide; Deschloronostocarboline iodide; Normelinonine F iodide

Chemical Property of 2-methylnorharman

Chemical Property:

• Vapor Pressure: 0.0011mmHg at 25°C
• Boiling Point: 300.8°C at 760 mmHg
• Flash Point: 142.2°C
• PSA: 15.27000
• LogP: 3.57030

Purity/Quality:

99% ^*data from raw suppliers

NORHARMAN METHIODIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-methylnorharman

There total 1 articles about 2-methylnorharman which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

betacarboline (244-63-3) + methyl iodide (74-88-4) → 2-methyl-β-carboline-2-ium iodide (5667-11-8)

Guidance literature:

In acetonitrile; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/chem.201103319

Reference yield: 98.0%

2-methyl-β-carboline-2-ium iodide (5667-11-8) → betacarboline (244-63-3)

Guidance literature:

With pyridine hydrochloride; for 10h; Heating;

DOI:10.1016/S0040-4039(97)01399-3

Reference yield: 34.0%

2-methyl-β-carboline-2-ium iodide (5667-11-8) → 1,2,3,4-tetrahydro-2-methyl-9H-pyrido[3,4-b]indole (13100-00-0)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1021/jm00122a031

upstream raw materials:

betacarboline

methyl iodide

Downstream raw materials:

1,2,3,4-tetrahydro-2-methyl-9H-pyrido[3,4-b]indole

betacarboline

Refernces

• 1、 Blom, Judith F.,Bruetsch, Tobias,Barbaras, Damien,Bethuel, Yann,Locher, Hans H.,Hubschwerlen, Christian,Gademann, Karl. "Potent algicides based on the cyanobacterial alkaloid nostocarboline". . p. 737 - 740. Retrieved 2006.
• 2、 Thatcher, Robert J.,Johnson, David G.,Slattery, John M.,Douthwaite, Richard E.. "Charged behaviour from neutral ligands: Synthesis and properties of N-heterocyclic pseudo-amides". experimental part. p. 4329 - 4336. Retrieved 2012/06/18.