Quinagolide

Base Information

• Chemical Name: Quinagolide
• CAS No.: 87056-78-8
• Molecular Formula: C20H33 N3 O3 S
• Molecular Weight: 395.62
• Nikkaji Number: J402.834A
• Wikipedia: Quinagolide
• Wikidata: Q4860568
• NCI Thesaurus Code: C73310
• Metabolomics Workbench ID: 152151
• ChEMBL ID: CHEMBL290962
• Mol file: 87056-78-8.mol

Synonyms:CV 205-502;CV-205-502;CV205-502;N,N-diethyl-N'-(1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzo(g)quinolinyl)sulfamide hydrochloride, (3alpha,4aalpha,10abeta)-(+)-isomer;N,N-diethyl-N'-(1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzo(g)quinolinyl)sulfamide, (3alpha,4aalpha,10abeta)-(+-)-isomer;Norprolac;quinagolide;quinagolide hydrochloride;quinagolide hydrochloride, (3alpha,4aalpha,10abeta)-(+)-isomer;quinagolide hydrochloride, 3alpha,4aalpha,10abeta-(-)-isomer;quinagolide, (3alpha,4aalpha,10abeta)-(+-)-isomer

Chemical Property of Quinagolide

Chemical Property:

• Vapor Pressure: 3.11E-12mmHg at 25°C
• Melting Point: 122.5-124°
• Boiling Point: 539.1°Cat760mmHg
• Flash Point: 279.8°C
• PSA: 81.26000
• Density: 1.23g/cm³
• LogP: 3.54570
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 395.22426310
• Heavy Atom Count: 27
• Complexity: 576

Purity/Quality:

99% ^*data from raw suppliers

QUINAGOLIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Human systemic effects reported. A reproductive hazard.
• Hazard Codes: Human systemic effects reported. A reproductive hazard.

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCN1CC(CC2C1CC3=C(C2)C(=CC=C3)O)NS(=O)(=O)N(CC)CC
• Isomeric SMILES: CCCN1C[C@H](C[C@H]2[C@H]1CC3=C(C2)C(=CC=C3)O)NS(=O)(=O)N(CC)CC
• Recent ClinicalTrials: Study Assessing the Effect of 3-week Treatment With One of Three Oral Doses of Quinagolide
• Recent EU Clinical Trials: A randomised, double-blind, placebo-controlled, proof-of-mechanism phase 2 trial investigating the effect of quinagolide extended-release vaginal ring on reduction of lesions assessed by high-resolution magnetic resonance imaging in women with endometrioma, deep infiltrating endometriosis, and/or adenomyosis
• Clinical Use: Hyperprolactinaemia
• Drug interactions: Potentially hazardous interactions with other drugs None known