L-TYROSINE ETHYL ESTER HYDROCHLORIDE

Base Information

• Chemical Name: L-TYROSINE ETHYL ESTER HYDROCHLORIDE
• CAS No.: 34081-17-9
• Molecular Formula: C11H15 N O3
• Molecular Weight: 209.245
• Hs Code.: 2922509090
• Mol file: 34081-17-9.mol

Synonyms:DL-Tyrosine,ethyl ester; Tyrosine, ethyl ester, DL- (8CI); NSC 138271

Chemical Property of L-TYROSINE ETHYL ESTER HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 3.59E-05mmHg at 25°C
• Melting Point: 166-170 °C
• Boiling Point: 343.3°Cat760mmHg
• Flash Point: 161.4°C
• PSA: 72.55000
• Density: 1.177g/cm³
• LogP: 1.52540
• Storage Temp.: −20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethyl2-amino-3-(4-hydroxyphenyl)propanoate 97% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-TYROSINE ETHYL ESTER HYDROCHLORIDE

There total 4 articles about L-TYROSINE ETHYL ESTER HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethanol (64-17-5) + ?Tyr (556-02-5,556-03-6,34537-57-0,55520-40-6,96946-98-4,60-18-4,18875-48-4,25619-78-7,30704-25-7) → tyrosine ethyl ester (34081-17-9)

Guidance literature:

ethanol; ?Tyr; With thionyl chloride; Reflux;

With sodium hydrogencarbonate;

DOI:10.1016/j.tetasy.2010.02.011

Reference yield:

tyrosine ethyl ester hydrochloride (5619-08-9) → tyrosine ethyl ester (34081-17-9)

Guidance literature:

tyrosine ethyl ester hydrochloride; With potassium carbonate; In dichloromethane; water; at 2 - 5 ℃; for 0.166667h;

With magnesium sulfate; In dichloromethane; for 1.16667h;

Reference yield:

?Tyr (556-02-5,556-03-6,34537-57-0,55520-40-6,96946-98-4,60-18-4,18875-48-4,25619-78-7,30704-25-7) → tyrosine ethyl ester (34081-17-9)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

?Tyr

ethanol

tyrosine ethyl ester hydrochloride

Downstream raw materials:

N-trifluoroacetyl-DL-tyrosine ethyl ester

N-acetyltyrosine

N-benzooxazol-2-yl-tyrosine ethyl ester

L-tyrosine

Refernces

• 1、 Stella, Selvaraj,Chadha, Anju. "Resolution of N-protected amino acid esters using whole cells of Candida parapsilosis ATCC 7330". experimental part. p. 457 - 460. Retrieved 2010/06/21.
• 2、 Watanabe, Ken-ichi,Yamada, Yoichi,Goto, Katsuhisa. "New Type of Aldol Condensations Catalyzed by Metal(II) Complexes of α-Amino Acid Esters and that with Cyclodextrin System". . p. 1401 - 1406. Retrieved 2007/10/02.