Methylphosphine

Base Information

• Chemical Name: Methylphosphine
• CAS No.: 593-54-4
• Molecular Formula: CH5 P
• Molecular Weight: 48.0245
• DSSTox Substance ID: DTXSID00208029
• Nikkaji Number: J95.053J
• Wikipedia: Methylphosphine
• Wikidata: Q10329188
• Metabolomics Workbench ID: 55228
• Mol file: 593-54-4.mol

Synonyms:Methylphosphine;Methylphosphane;Phosphine, methyl-;MePH2;593-54-4;METHYLPHOSPHIN;phosphonium methylide;PMeH2;CH5P;CH3PH2;C-H5-P;CHEBI:35887;DTXSID00208029;AKOS006279376;Q10329188

Chemical Property of Methylphosphine

Chemical Property:

• Vapor Pressure: 2810mmHg at 25°C
• Boiling Point: -16°C
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 48.012887157
• Heavy Atom Count: 2
• Complexity: 2

Purity/Quality:

99%, ^*data from raw suppliers

METHYLPHOSPHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CP

Technology Process of Methylphosphine

There total 34 articles about Methylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

dimethyl methane phosphonate (756-79-6) → methylphosphine (593-54-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetraglyme; Inert atmosphere; Cooling;

DOI:10.1039/b804780d

Reference yield: 87.0%

Diethyl methylphosphonate (683-08-9) → methylphosphine (593-54-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetraethylene glycol dimethyl ether; at -10 ℃;

DOI:10.1002/chem.200802307

Reference yield: 80.0%

diphenyl (chloromethyl)phosphonate (10419-85-9) → methylphosphine (593-54-4) + 1-chloromethylphosphine (7237-08-3)

Guidance literature:

With aluminium hydride; In various solvent(s); for 1h; Yields of byproduct given; Ambient temperature;

upstream raw materials:

methylene chloride

chloroform

methyl iodide

methyl bromide

Downstream raw materials:

Bis-diethylamino-(methyl-phosphino)-methyl-silan

(2-Chloro-1,1,3,3-tetrafluoro-allyl)-methyl-phosphane

1-[Methyl-(2-phosphanyl-ethyl)-phosphanyl]-2-phosphanyl-ethane

Bis--methyl-phosphin

Refernces

• 1、 Wagner,Burg. "-". . p. 3869,3871. Retrieved 1953.
• 2、 Jolly. "". . p. 126. Retrieved 1968.
• 3、 Hurtado, Marcela,Yanez, Manuel,Herrero, Rebeca,Guerrero, Andres,Juan Z. Davalos,Jose-Luis, M. Abboud,Khater, Brahim,Guillemin, Jean-Claude. "The Ever-surprising chemistry of boron: Enhanced acidity of phosphine·boranes". supporting information; experimental part. p. 4622 - 4629. Retrieved 2009/12/29.
• 4、 Noble-Eddy, Robert,Masters, Sarah L.,Rankin, David W. H.,Wann, Derek A.,Khater, Brahim,Guillemin, Jean-Claude. "More user-friendly phosphines? Molecular structure of methylphosphine and its adduct with borane, studied by gas-phase electron diffraction and quantum chemical calculations". supporting information; experimental part. p. 5041 - 5047. Retrieved 2009/02/06.