3,3'-Oxydipropionyl dichloride

Base Information

• Chemical Name: 3,3'-Oxydipropionyl dichloride
• CAS No.: 44995-78-0
• Molecular Formula: C6H8Cl2O3
• Molecular Weight: 199.034
• Hs Code.: 2918990090
• European Community (EC) Number: 256-177-1
• DSSTox Substance ID: DTXSID20196358
• Nikkaji Number: J319.939H
• Wikidata: Q83069424
• Mol file: 44995-78-0.mol

Synonyms:3,3'-Oxydipropionyl dichloride;44995-78-0;EINECS 256-177-1;3-(3-chloro-3-oxopropoxy)propanoyl chloride;DTXSID20196358;3,3'-Oxybis(propanoic acid chloride)

Chemical Property of 3,3'-Oxydipropionyl dichloride

Chemical Property:

• Boiling Point: 254.4oC at 760 mmHg
• Flash Point: 108.1oC
• PSA: 43.37000
• Density: 1.318g/cm3
• LogP: 1.31400
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 197.9850495
• Heavy Atom Count: 11
• Complexity: 131

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(COCCC(=O)Cl)C(=O)Cl

Technology Process of 3,3'-Oxydipropionyl dichloride

There total 3 articles about 3,3'-Oxydipropionyl dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-cyanoethyl ether (1656-48-0) → 3,3'oxybispropionic acid dichloride (44995-78-0)

Guidance literature:

With hydrogenchloride; In water; at 50 ℃; for 24h;

DOI:10.1002/hlca.19800630117

Reference yield: 74.0%

3-(2-carboxyethoxy)propionic acid (5961-83-1) → 3,3'oxybispropionic acid dichloride (44995-78-0)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; In benzene; 1.) 40 deg C, 9 h, 2.) RT; 15 h;

DOI:10.1002/hlca.19800630117

Reference yield:

→ 3,3'oxybispropionic acid dichloride (44995-78-0)

Guidance literature:

entspr.S.;

DOI:10.1021/jo00444a032

upstream raw materials:

3-(2-carboxyethoxy)propionic acid

2-cyanoethyl ether

Downstream raw materials:

N,N,N',N'-Tetraphenyl-4-oxaheptandiamid

C₆₆H₉₄N₆O₁₄S₂

C₄₅H₅₇N₃O₁₂

5,13-bis(4'-methoxycarbonylbenzoyl)-21-tosyl-1,9,17-trioxa-5,13,21-triazacyclotetracosane

Refernces

• 1、 Iqbal, Mudassir,Huskens, Jurriaan,Verboom, Willem,Sypula, Michal,Modolo, Giuseppe. "Synthesis and Am/Eu extraction of novel TODGA derivatives". scheme or table. p. 827 - 837. Retrieved 2011/12/02.
• 2、 Pratt, John A. E.,Sutherland, Ian O.,Newton, Roger F.. "MACROCYCLIC AND MACROPOLYCYCLIC COMPOUNDS BASED UPON 1,3-DISUBSTITUTED PROPANE UNITS". . p. 13 - 22. Retrieved 2007/10/02.