CIS-1,4-CYCLOHEXANEDIOL

Base Information

• Chemical Name: CIS-1,4-CYCLOHEXANEDIOL
• CAS No.: 931-71-5
• Molecular Formula: C6H12O2
• Molecular Weight: 116.16
• Hs Code.: 2906199090
• Mol file: 931-71-5.mol

Synonyms:CIS-1,4-CYCLOHEXANEDIOL;cis-cyclohexane-1,4-diol;TRANS-1,4-CYLCLOHEXANEDIOL;cis-4-cyclohexanediol

Chemical Property of CIS-1,4-CYCLOHEXANEDIOL

Chemical Property:

• Melting Point: 98-100 ºC
• Boiling Point: 252.4°Cat760mmHg
• PKA: 14.75±0.40(Predicted)
• Flash Point: 65 ºC
• PSA: 40.46000
• Density: 1.156g/cm³
• LogP: 0.28220
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-1,4-Cyclohexanediol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: cis-1,4-Cyclohexanediol is an metabolite of side-chain of candesartan cilexetil (C175580), on digoxin-induced arrhythmias in dogs with congestive heart failure. cis-1,4-Cyclohexanediol is a metabolite of the side-chain of candesartan cilexetil (C175580), on digoxin-induced arrhythmias in dogs with congestive heart failure.

Technology Process of CIS-1,4-CYCLOHEXANEDIOL

There total 55 articles about CIS-1,4-CYCLOHEXANEDIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.3%

C14H18O4 → cis-1,4-cyclohexanediol (931-71-5)

Guidance literature:

With water; sodium hydroxide; In methanol; at -15 ℃; for 14h;

Reference yield: 94.2%

C15H20O3 → cis-1,4-cyclohexanediol (931-71-5)

Guidance literature:

With water; lithium hydroxide; In ethanol; at -5 ℃; for 10h;

Reference yield: 93.1%

C14H17ClO3 → cis-1,4-cyclohexanediol (931-71-5)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; at -10 ℃; for 12h;

upstream raw materials:

cis-1,4-diacetoxy-cyclohexane

cyclohexa-1,3-diene

hydroquinone

7-oxabicyclo(2.2.1)heptane

Downstream raw materials:

trans-1,4-bis-(propane-1-sulfonyloxy)-cyclohexane

3-cyclohexen-1-ol

1-phenyl-1-cyclohexane

cyclohexane-1,4-diol

Refernces

• 1、 -. "Synthetic method for cis-1,4-cyclohexanediol". . . Retrieved 2018/03/24.
• 2、 Erden, Ihsan,Gaertner, Christian,Saeed Azimi. "Triphenylphosphine reduction of saturated endoperoxides". supporting information; experimental part. p. 3986 - 3989. Retrieved 2009/12/05.