Dymanthine

Base Information

• Chemical Name: Dymanthine
• CAS No.: 124-28-7
• Molecular Formula: C20H43N
• Molecular Weight: 297.568
• Hs Code.: 29211999
• European Community (EC) Number: 204-694-8
• UN Number: 2735
• UNII: 066975NG22
• DSSTox Substance ID: DTXSID4027026
• Nikkaji Number: J5.548D
• Wikidata: Q24817440
• NCI Thesaurus Code: C65393
• ChEMBL ID: CHEMBL2110847
• Mol file: 124-28-7.mol

Synonyms:dimantin;dymanthine;dymanthine hydrochloride;N,N-dimethyl-n-octadecylamine;thelmesan

Chemical Property of Dymanthine

Chemical Property:

• Appearance/Colour: Solid
• Vapor Pressure: 5.03E-05mmHg at 25°C
• Melting Point: 23 °C
• Refractive Index: 1.45
• Boiling Point: 348.5 °C at 760 mmHg
• PKA: 9.78±0.28(Predicted)
• Flash Point: 153.8 °C
• PSA: 3.24000
• Density: 0.813 g/cm³
• LogP: 6.80950
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: Chloroform (Slightly), Hexanes (Slightly)
• Water Solubility.: Slightly soluble
• XLogP3: 9.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 17
• Exact Mass: 297.339550376
• Heavy Atom Count: 21
• Complexity: 177
• Transport DOT Label: Corrosive

Purity/Quality:

98% ^*data from raw suppliers

N,N-Dimethyloctadecan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-22
• Safety Statements: 45-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CCCCCCCCCCCCCCCCCCN(C)C
• Uses: N,N-Dimethyloctadecylamine is used as chemical intermediates for the manufacture of quaternary ammonium compounds, amine oxide and betaine surfactants N,N-Dimethyloctadecan-1-amine is a useful reagent for the preparation of cationic gelatin cross-linked with Tannic Acid (T006560(P)).

Technology Process of Dymanthine

There total 14 articles about Dymanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.3%

1-octadecanol (112-92-5) + dimethyl amine (124-40-3) → N,N-dimethyl-n-octadecylamine (124-28-7)

Guidance literature:

With hydrogen; at 225 ℃; for 4.2h; under 772.577 - 1200.12 Torr;

Reference yield: 85.0%

N-(3-(diethylamino)benzyl)-N,N-dimethyloctadecan-1-aminium chloride → N,N-dimethyl-n-octadecylamine (124-28-7)

Guidance literature:

In water; acetonitrile; for 0.25h; Solvent; Irradiation;

DOI:10.1021/acs.joc.6b00508

Reference yield: 81.7%

N,N-dimethyloctadecanamide (3886-90-6) → N,N-dimethyl-n-octadecylamine (124-28-7)

Guidance literature:

With hydrogen; sponge copper catalyst: 73.4percent Cu, 0.5percent Mg, 5.7percent Fe, 0.9percent Al; In water; at 250 ℃; under 11251.1 Torr; Inert atmosphere; Autoclave;

upstream raw materials:

1-octadecanol

dimethyl amine

1-Bromooctadecane

formaldehyd

Downstream raw materials:

trimethyloctadecylammonium chloride

n-octadecylbenzyldimethylammonium iodide

dimethyldifluorosilane

trimethylstearylammoniumperfluorooctylsulfonate

Refernces

• 1、 Hall,Griffin,Docks,Brotherton,Futch. "Hypolipidemic activity of N,N-dimethyl-n-octadecylamine borane in rodents". . p. 706 - 710. Retrieved 1986.
• 2、 -. "TERTIARY AMINE PREPARATION PROCESS". Paragraph 0104-0106; 0119-0121. . Retrieved 2013/11/06.
• 3、 -. "PROCESS FOR PRODUCING NITROGEN-CONTAINING COMPOUNDS". Page/Page column 6. . Retrieved 2010/08/03.