2-(2,4-Dinitrophenylhydrazono)propionic acid

Base Information

• Chemical Name: 2-(2,4-Dinitrophenylhydrazono)propionic acid
• CAS No.: 790-12-5
• Molecular Formula: C9H8N4O6
• Molecular Weight: 268.186
• NSC Number: 407330
• DSSTox Substance ID: DTXSID501031334
• Nikkaji Number: J1.018.889J
• Mol file: 790-12-5.mol

Synonyms:2-(2,4-Dinitrophenylhydrazono)propionic acid;790-12-5;(2Z)-2-[(2,4-dinitrophenyl)hydrazinylidene]propanoic acid;Pyruvic acid 2,4-dinitrophenylhydrazone;NSC407330;CVWXLIFTNILJFS-YHYXMXQVSA-N;DTXSID501031334;NSC-407330;2-[(Z)-2,4-dinitro-phenylhydrazono]-propionic acid;(2Z)-2-[(2,4-Dinitrophenyl)hydrazono]propanoic acid #;20724-92-9

Chemical Property of 2-(2,4-Dinitrophenylhydrazono)propionic acid

Chemical Property:

• Vapor Pressure: 1.24E-09mmHg at 25°C
• Boiling Point: 469.9°C at 760 mmHg
• Flash Point: 238°C
• PSA: 153.33000
• Density: 1.64g/cm³
• LogP: 2.49480
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 268.04438399
• Heavy Atom Count: 19
• Complexity: 412

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NNC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-])C(=O)O
• Isomeric SMILES: C/C(=N/NC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-])/C(=O)O

Technology Process of 2-(2,4-Dinitrophenylhydrazono)propionic acid

There total 5 articles about 2-(2,4-Dinitrophenylhydrazono)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nε-[(R)-1-carboxyethyl]-L-lysine (68852-49-3,68852-50-6,104012-68-2,5746-03-2) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → L-lysine (56-87-1,3506-25-0) + 2-(2,4-dinitrophenylhydrazono)-propanoic acid (790-12-5)

Guidance literature:

N^ε-[(R)-1-carboxyethyl]-L-lysine; With Escherichia coli wild-type didomain MnmC enzyme; water; oxygen; flavin adenine dinucleotide; In aq. phosphate buffer; at 37 ℃; pH=7.4; Enzymatic reaction;

(2,4-dinitro-phenyl)-hydrazine; With hydrogenchloride; In water; at 37 ℃; for 0.166667h;

DOI:10.1002/cbic.201900158

Reference yield:

2-oxo-propionic acid (127-17-3) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 2-(2,4-dinitrophenylhydrazono)-propanoic acid (790-12-5)

Guidance literature:

With hydrogenchloride; In methanol; at 60 ℃; for 0.5h;

DOI:10.1271/bbb.65.2695

Reference yield:

diketopiperazine–CEL + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 2-(2,4-dinitrophenylhydrazono)-propanoic acid (790-12-5)

Guidance literature:

diketopiperazine–CEL; With Escherichia coli wild-type didomain MnmC enzyme; water; oxygen; flavin adenine dinucleotide; In aq. phosphate buffer; at 37 ℃; pH=7.4; Enzymatic reaction;

(2,4-dinitro-phenyl)-hydrazine; With hydrogenchloride; In water; at 37 ℃; for 0.166667h;

DOI:10.1002/cbic.201900158

upstream raw materials:

ethyl acetate

oxaloacetic acid 2,4-dinitrophenylhydrazone

2-oxo-propionic acid

(2,4-dinitro-phenyl)-hydrazine

Downstream raw materials:

2-(2,4-dinitro-phenylhydrazono)-propionyl chloride

Brenztraubensaeure-methylester-(2,4-dinitro-phenylhydrazon)

2-((E)-2,4-dinitro-phenylhydrazono)-propionic acid methyl ester

2-((Z)-2,4-dinitro-phenylhydrazono)-propionic acid methyl ester

Refernces

• 1、 Swami, Preeti,Yajurvedi,Mishra,Sharma, Pradeep K.. "Oxidation of some α-hydroxy acids by tetraethylammonium chlorochromate: A kinetic and mechanistic study". experimental part. p. 50 - 55. Retrieved 2010/04/06.
• 2、 Choudhary,Yajurvedi,Kumbhani,Shastri,Sharma, Vinita. "Oxidation of some unsaturated acids by tetrakis (pyridine) silver dichromate: A kinetic and mechanistic study". experimental part. p. 832 - 836. Retrieved 2010/06/12.