1-(2-BROMOETHYL)NAPHTHALENE

Base Information

• Chemical Name: 1-(2-BROMOETHYL)NAPHTHALENE
• CAS No.: 13686-49-2
• Molecular Formula: C12H11 Br
• Molecular Weight: 235.123
• Hs Code.: 29036990
• European Community (EC) Number: 624-931-2
• DSSTox Substance ID: DTXSID20159983
• Nikkaji Number: J986.196C
• Wikidata: Q83028359
• Mol file: 13686-49-2.mol

Synonyms:1-(2-Bromoethyl)naphthalene;1-Bromo-2-(1-naphthyl)ethane; 2-(1-Naphthyl)-1-bromoethane; 2-(1-Naphthyl)ethylbromide; 2-a-Naphthylethyl bromide

Chemical Property of 1-(2-BROMOETHYL)NAPHTHALENE

Chemical Property:

• Appearance/Colour: COLORLESS LIQUID
• Vapor Pressure: 0.000701mmHg at 25°C
• Melting Point: 37-40 °C (decomp)
• Refractive Index: n20/D 1.638(lit.)
• Boiling Point: 237-238 °C760 mm Hg(lit.)
• Flash Point: >230 °F
• PSA: 0.00000
• Density: 1.646 g/mL at 25 °C(lit.)
• LogP: 3.77720
• Water Solubility.: It is slightly soluble in water.
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 234.00441
• Heavy Atom Count: 13
• Complexity: 155

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(2-Bromoethyl)naphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2CCBr
• Uses: 1-(2-Bromoethyl)naphthalene has applications in research field such as Western blotting, Immunoprecipitation, immunogen, and in purification, process.

Technology Process of 1-(2-BROMOETHYL)NAPHTHALENE

There total 10 articles about 1-(2-BROMOETHYL)NAPHTHALENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-naphthaleneethanol (773-99-9) → 1-(2-bromo)ethylnaphthalene (13686-49-2)

Guidance literature:

With phosphorus tribromide; In toluene; for 5h; Reflux;

DOI:10.1002/anie.201611823

Reference yield: 73.0%

→ 1-(2-bromo)ethylnaphthalene (13686-49-2)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 2.16667h;

Reference yield:

naphth-1-yl acetic acid (86-87-3) → 1-(2-bromo)ethylnaphthalene (13686-49-2)

Guidance literature:

With indium(III) bromide; 1,1,3,3-Tetramethyldisiloxane; trimethylsilyl cyanide; In chloroform; at 60 ℃; Inert atmosphere;

DOI:10.1055/s-0033-1339903

upstream raw materials:

2-naphthaleneethanol

acetic acid

ethyl 2-(1-naphthyl)acetate

2-(3,4-dihydro-naphthalen-1-yl)-acetic acid ethyl ester

Downstream raw materials:

2--4--butyronitril

4-(1-naphthyl)butanoic acid

3,4,5-Trimethoxy-benzoesaeure-naphthyl-aethyl)-amid>

methyl 5-(cyano[2-(1-naphthyl)ethyl]methyl)-3-tetrahydropyranyl-imidazole-4-carboxylate

Refernces

• 1、 Xie, Qiqiang,Ni, Chuanfa,Zhang, Rongyi,Li, Lingchun,Rong, Jian,Hu, Jinbo. "Efficient Difluoromethylation of Alcohols Using TMSCF2Br as a Unique and Practical Difluorocarbene Reagent under Mild Conditions". supporting information. p. 3206 - 3210. Retrieved 2017/03/17.
• 2、 Tresse, Cedric,Guissart, Celine,Schweizer, Stephane,Bouhoute, Yassine,Chany, Anne-Caroline,Goddard, Mary-Lorene,Blanchard, Nicolas,Evano, Gwilherm. "Practical methods for the synthesis of trifluoromethylated alkynes: Oxidative trifluoromethylation of copper acetylides and alkynes". supporting information. p. 2051 - 2060. Retrieved 2014/07/07.