Cytidine 2',3'-cyclic phosphate

Base Information

• Chemical Name: Cytidine 2',3'-cyclic phosphate
• CAS No.: 15718-51-1
• Molecular Formula: C9H12N3NaO7P
• Molecular Weight: 327.166
• Mol file: 15718-51-1.mol

Synonyms:Cytidine 2',3'-cyclic phosphate;2',3' cyclic CMP;2',3' cyclic-CMP;Cyclic(2',3')-CMP;cytidine-2',3'-cyclophosphate;CHEBI:177258;1-[(3aR,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-oxo-3a,4,6,6a-tetrahydrouro[3,4-d][1,3,2]dioxaphosphol-4-yl]-4-aminopyrimidin-2-one

Chemical Property of Cytidine 2',3'-cyclic phosphate

Chemical Property:

• Boiling Point: 568.5 °C at 760 mmHg
• Flash Point: 297.6 °C
• PSA: 158.77000
• Density: 2.28 g/cm³
• LogP: -0.38100
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
• XLogP3: -3.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 305.04128673
• Heavy Atom Count: 20
• Complexity: 550

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cytidine 2′:3′-cyclic monophosphate monosodium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CN(C(=O)N=C1N)C2C3C(C(O2)CO)OP(=O)(O3)O
• Isomeric SMILES: C1=CN(C(=O)N=C1N)C2[C@H]3[C@@H]([C@H](O2)CO)OP(=O)(O3)O
• Uses: Cytidine 2’3’Cyclic Monophosphate is a key compound in the enzymic synthesis of short oligoribonucleotides. Cytidine 2′,3′-cyclic monophosphate (2′,3′-CyclicCMP) (2′,3′-cCMP) is used as a model substrate for kinetic analysis of various ribonucleases, especially ribonuclease A.

Technology Process of Cytidine 2',3'-cyclic phosphate

There total 3 articles about Cytidine 2',3'-cyclic phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

CYTIDINE (65-46-3) → cytidine 2′,3′-cyclic monophosphate sodium salt (15718-51-1)

Guidance literature:

With 1H-imidazole; sodium diamido phosphate; water; at 20 ℃; for 240h; pH=5.5;

DOI:10.1038/nchem.2878

Reference yield:

cytidine-3'-monophosphate dinatrium salt → cytidine 2′,3′-cyclic monophosphate sodium salt (15718-51-1)

Guidance literature:

With sodium diamido phosphate; water;

DOI:10.1038/nchem.2878

Reference yield:

C9H12N3O8P(2-)*2Na(1+) → cytidine 2′,3′-cyclic monophosphate sodium salt (15718-51-1)

Guidance literature:

With sodium diamido phosphate; water;

DOI:10.1038/nchem.2878

upstream raw materials:

CYTIDINE

Refernces