Linoleylamine

Base Information

• Chemical Name: Linoleylamine
• CAS No.: 25876-34-0
• Molecular Formula: C18H35 N
• Molecular Weight: 265.4772
• Hs Code.: 2921199090
• UNII: 6UR1N0Y2KZ
• DSSTox Substance ID: DTXSID20885316
• Wikidata: Q27265550
• Mol file: 25876-34-0.mol

Synonyms:Linoleylamine;Linoleamine;25876-34-0;UNII-6UR1N0Y2KZ;6UR1N0Y2KZ;9,12-Octadecadien-1-amine, (9Z,12Z)-;9,12-Octadecadienylamine, (Z,Z)-;9,12-Octadecadien-1-amine, (Z,Z)-;Linoleyl Amine;SCHEMBL417357;DTXSID20885316;GOLAKLHPPDDLST-HZJYTTRNSA-N;Q27265550

Chemical Property of Linoleylamine

Chemical Property:

• Vapor Pressure: 1.41E-05mmHg at 25°C
• Boiling Point: 367°Cat760mmHg
• Flash Point: 157.1°C
• PSA: 26.02000
• Density: 0.838g/cm³
• LogP: 6.45890
• XLogP3: 6.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 14
• Exact Mass: 265.276950121
• Heavy Atom Count: 19
• Complexity: 206

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC=CCC=CCCCCCCCCN
• Isomeric SMILES: CCCCC/C=C\C/C=C\CCCCCCCCN

Technology Process of Linoleylamine

There total 9 articles about Linoleylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

linoleyl phthalimide → (9Z,12Z)-octadecane-9,12-dien-1-amine (25876-34-0)

Guidance literature:

With hydrazine; In ethanol; at 85 - 90 ℃; for 2h;

Reference yield: 69.0%

linoleamide (3999-01-7,3072-13-7) → (9Z,12Z)-octadecane-9,12-dien-1-amine (25876-34-0)

Guidance literature:

With bis(cyclopentadienyl)dihydrozirconium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In dichloromethane; at 20 ℃; for 16h; under 760.051 Torr; Inert atmosphere;

Reference yield:

(9Z,12Z)-octadeca-9,12-dienyl methanesulfonate (51154-39-3) → (9Z,12Z)-octadecane-9,12-dien-1-amine (25876-34-0)

Guidance literature:

With ammonia; In methanol; at 150 ℃; for 1.5h; Microwave irradiation;

upstream raw materials:

linoleamide

octadeca-9,12-dienoic acid ethyl ester

linoleyl azide

(9Z,12Z)-octadeca-9,12-dienyl methanesulfonate

Refernces

• 1、 -. "Method for preparing amine compound by reducing amide compound". Paragraph 0289-0291. . Retrieved 2021/02/10.
• 2、 Kuboyama, Takeshi,Yagi, Kaori,Naoi, Tomoyuki,Era, Tomohiro,Yagi, Nobuhiro,Nakasato, Yoshisuke,Yabuuchi, Hayato,Takahashi, Saori,Shinohara, Fumikazu,Iwai, Hiroto,Koubara-Yamada, Ayumi,Hasegawa, Kazumasa,Miwa, Atsushi. "Simplifying the Chemical Structure of Cationic Lipids for siRNA-Lipid Nanoparticles". supporting information. p. 749 - 753. Retrieved 2019/05/06.