2-Decenoic acid, 10-hydroxy-

Base Information

• Chemical Name: 2-Decenoic acid, 10-hydroxy-
• CAS No.: 765-01-5
• Molecular Formula: C10H18 O3
• Molecular Weight: 186.251
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID50997870
• Mol file: 765-01-5.mol

Synonyms:10-HDEC;10-hydroxy-2-decenoic acid;10-hydroxy-2-decenoic acid, (E)-isomer;10-hydroxy-2-decenoic acid, monopotassium salt;10-hydroxy-2-decenoic acid, monosodium salt;10-hydroxy-2-decenoic acid, sodium salt;Hydroxydecine

Chemical Property of 2-Decenoic acid, 10-hydroxy-

Chemical Property:

• Appearance/Colour: White or type of white crystals
• Vapor Pressure: 6.5E-06mmHg at 25°C
• Melting Point: 53-55 ºC
• Refractive Index: 1.465
• Boiling Point: 339.2 °C at 760 mmHg
• PKA: 4.78±0.10(Predicted)
• Flash Point: 173.1 °C
• PSA: 57.53000
• Density: 1.038 g/cm³
• LogP: 1.96010
• Storage Temp.: 2-8°C
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 186.125594432
• Heavy Atom Count: 13
• Complexity: 152

Purity/Quality:

99.9% ^*data from raw suppliers

Royal jelly acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCC=CC(=O)O)CCCO

Technology Process of 2-Decenoic acid, 10-hydroxy-

There total 10 articles about 2-Decenoic acid, 10-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C10H17BrO2 → 10-hydroxy-2-decenoic acid (765-01-5)

Guidance literature:

C₁₀H₁₇BrO₂; With sodium hydroxide; In ethanol; at 20 ℃; for 3h;

With hydrogenchloride; In water; pH=4; Time;

Reference yield: 71.0%

C12H22O3 (64971-15-9) → 10-hydroxy-2-decenoic acid (765-01-5)

Guidance literature:

C₁₂H₂₂O₃; With sodium carbonate; In tetrahydrofuran; water; at 65 ℃; for 3h;

With hydrogenchloride; water; In tetrahydrofuran; pH=2;

Reference yield:

10-hydroxy 8-decenoic acid ethyl ester (57221-93-9) → 10-hydroxy-2-decenoic acid (765-01-5)

Guidance literature:

With potassium hydroxide; In ethanol; for 0.5h; Yield given; Heating;

upstream raw materials:

malonic acid

8,8-diethoxy-octan-1-ol

10-hydroxy 8-decenoic acid ethyl ester

8-hydroxyoctanal

Refernces

• 1、 -. "NOVEL CERAMIDE ANALOGUES, PROCESSES FOR PREPARING SAME AND USES THEREOF". Paragraph 0247-0252. . Retrieved 2014/09/16.
• 2、 Villieras, J.,Rambaud, M.,Graff, M.. "WITTIG-HORNER REACTION IN HETEROGENOUS MEDIA VII. A NEW STRATEGY FOR THE TOTAL SYNTHESIS OF THE ROYAL JELLY ACID AND THE QUEEN SUBSTANCE OF HONEY-BEE". . p. 569 - 580. Retrieved 2007/10/02.