1,2-Benzisothiazole-2(3H)-acetamide, N-(4-hydroxyphenyl)-3-oxo-, 1,1-dioxide

Base Information Edit

Chemical Name:1,2-Benzisothiazole-2(3H)-acetamide, N-(4-hydroxyphenyl)-3-oxo-, 1,1-dioxide
CAS No.:182502-68-7
Molecular Formula:C15H12N2O5S
Molecular Weight:332.337
Hs Code.:
UNII:1D7315Y2YS
Nikkaji Number:J1.050.107E
ChEMBL ID:CHEMBL239901
Mol file:182502-68-7.mol

Synonyms:N-(alpha-(1,2-benzisothiazol-3(2H)-ona-1,1-dioxide-2-yl)acetyl)-p-aminophenol;SCP 1;SCP-1

Suppliers and Price of 1,2-Benzisothiazole-2(3H)-acetamide, N-(4-hydroxyphenyl)-3-oxo-, 1,1-dioxide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2-Benzisothiazole-2(3H)-acetamide, N-(4-hydroxyphenyl)-3-oxo-, 1,1-dioxide Edit

Chemical Property:

PSA：112.16000
LogP:2.26710
Storage Temp.:-20°C
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:332.04669266
Heavy Atom Count:23
Complexity:577

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(S2(=O)=O)CC(=O)NC3=CC=C(C=C3)O

Technology Process of 1,2-Benzisothiazole-2(3H)-acetamide, N-(4-hydroxyphenyl)-3-oxo-, 1,1-dioxide

There total 3 articles about 1,2-Benzisothiazole-2(3H)-acetamide, N-(4-hydroxyphenyl)-3-oxo-, 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 2153-11-9
4-chloroacetamidophenol

: 128-44-9
saccharin sodium salt

: 182502-68-7
SCP-1

Guidance literature:: In N,N-dimethyl-formamide; for 2h; Heating;
DOI:10.1016/j.bmc.2006.07.054

Reference yield:

: 123-30-8
4-amino-phenol

: 182502-68-7
SCP-1

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / acetic acid; sodium acetate / H₂O / 2 h / 0 °C

2: 86 percent / dimethylformamide / 2 h / Heating

With sodium acetate; acetic acid; In water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2006.07.054