D-Glucosamine sulfate

Base Information

• Chemical Name: D-Glucosamine sulfate
• CAS No.: 29031-19-4
• Deprecated CAS: 216447-61-9
• Molecular Formula: C6H13NO5^.H2SO4
• Molecular Weight: 456.425
• Hs Code.: 2932999099
• European Community (EC) Number: 249-379-6
• DSSTox Substance ID: DTXSID30944241
• NCI Thesaurus Code: C29075
• RXCUI: 4847
• Mol file: 29031-19-4.mol

Synonyms:2 Amino 2 Deoxyglucose;2-Amino-2-Deoxyglucose;Dona;Dona S;Glucosamine;Glucosamine Sulfate;Hespercorbin;Sulfate, Glucosamine;Xicil

Chemical Property of D-Glucosamine sulfate

Chemical Property:

• Appearance/Colour: white crystal
• Vapor Pressure: 5.53E-10mmHg at 25°C
• Melting Point: 176°C
• Boiling Point: 449.9 °C at 760 mmHg
• Flash Point: 225.9 °C
• PSA: 206.99000
• Density: 1.563 g/cm³
• LogP: -2.28410
• Storage Temp.: -20?C Freezer
• Solubility.: Soluble at 1mg/ml in 1M HCl
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 5
• Exact Mass: 277.04675223
• Heavy Atom Count: 17
• Complexity: 223

Purity/Quality:

99% ^*data from raw suppliers

D-Glucosamine Sulfate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(C(C(C=O)N)O)O)O)O.OS(=O)(=O)O
• Isomeric SMILES: C([C@H]([C@H]([C@@H]([C@H](C=O)N)O)O)O)O.OS(=O)(=O)O
• Recent ClinicalTrials: Prescription-grade Crystalline Glucosamine Sulfate Therapy in Erosive Hand Osteoarthritis
• Recent EU Clinical Trials: Effect of anastrozole on arthralgia and the effect of glucosamine sulphate supplementation in postmenopausal women with arthralgia in the IBIS-II breast cancer prevention trial
• Uses: Novel application of glucosamine to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Pharmaceutic aid. D-Glucosamine Sulfate is used on the syntheis of aryl β-N-acetylglucosaminides modified at C-6 as potential antimicrobial agents.

Technology Process of D-Glucosamine sulfate

There total 1 articles about D-Glucosamine sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-deoxy-2-amino glucose (90-76-6,90-77-7,530-23-4,579-32-8,579-33-9,643-68-5,2596-19-2,6490-68-2,6490-70-6,6490-72-8,6490-73-9,6490-74-0,14196-84-0,14196-86-2,14257-69-3,58381-21-8) → 2-amino-2-deoxyglucose sulfate (29031-19-4)

Guidance literature:

With sulfuric acid; In water; at 5 - 10 ℃; for 0.5h; pH=3.5; Product distribution / selectivity; polyethylene glycol homopolymer (Mw=4000);

upstream raw materials:

2-deoxy-2-amino glucose

Refernces