3-Ethyl-2-phenylpyridine

Base Information

• Chemical Name: 3-Ethyl-2-phenylpyridine
• CAS No.: 85237-70-3
• Molecular Formula: C13H13N
• Molecular Weight: 183.253
• Hs Code.: 2933399090
• European Community (EC) Number: 286-431-7
• DSSTox Substance ID: DTXSID00234449
• Nikkaji Number: J307.607E
• Wikidata: Q83116244
• Mol file: 85237-70-3.mol

Synonyms:3-Ethyl-2-phenylpyridine;85237-70-3;EINECS 286-431-7;3-Ethyl-2-phenyl-pyridine;SCHEMBL13869175;DTXSID00234449

Chemical Property of 3-Ethyl-2-phenylpyridine

Chemical Property:

• Vapor Pressure: 0.000932mmHg at 25°C
• Refractive Index: 1.56
• Boiling Point: 313.1 °C at 760 mmHg
• Flash Point: 133.8 °C
• PSA: 12.89000
• Density: 1.013 g/cm³
• LogP: 3.31100
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 183.104799419
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=C(N=CC=C1)C2=CC=CC=C2

Technology Process of 3-Ethyl-2-phenylpyridine

There total 2 articles about 3-Ethyl-2-phenylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

propiophenone (495-40-9) + Trimethylenediamine (109-76-2,54018-94-9) → 3-ethyl-2-phenylpyridine (85237-70-3)

Guidance literature:

With oxygen; copper(II) bis(trifluoromethanesulfonate); toluene-4-sulfonic acid; In hexan-1-ol; at 110 ℃; for 24h; Sealed tube; Schlenk technique;

DOI:10.1021/ol5023596

Reference yield:

→ 3-ethyl-2-phenylpyridine (85237-70-3)

Guidance literature:

Aus 3-Ethyl-pyridin, Phenyllithium, Ae.; als Hauptprodukt;

DOI:10.1139/v62-036

upstream raw materials:

propiophenone

Trimethylenediamine

Refernces