(2,5-dioxopyrrolidin-1-yl) N-Methyl-N-nitrosocarbaMate

Base Information

• Chemical Name: (2,5-dioxopyrrolidin-1-yl) N-Methyl-N-nitrosocarbaMate
• CAS No.: 80354-48-9
• Molecular Formula: C6H7N3O5
• Molecular Weight: 201.1369
• Mol file: 80354-48-9.mol

Synonyms:Methylnitrosocarbamic acid 2,5-dioxo-1-pyrrolidinyl ester;2,5-Pyrrolidinedione,1-(((methylnitrosoamino)carbonyl)oxy);ICIG 1732;N-methyl-N-nitrosocarbamic acid N'-hydroxysuccinimide ester;N-Methyl N-nitroso-carbamate de succinimidyle [French];N-methyl N-nitroso-carbamate de succinimidyle;CARBAMIC ACID,METHYLNITROSO-2,5-DIOXO-1-PYRROLIDINYL ESTER;

Chemical Property of (2,5-dioxopyrrolidin-1-yl) N-Methyl-N-nitrosocarbaMate

Chemical Property:

• Vapor Pressure: 0.0027mmHg at 25°C
• Boiling Point: 286.1°Cat760mmHg
• Flash Point: 126.8°C
• PSA: 96.35000
• Density: 1.65g/cm³
• LogP: -0.26190

Purity/Quality:

99% ^*data from raw suppliers

METHYLNITROSOCARBAMIC ACID 2,5-DIOXO-1-PYRROLIDINYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2,5-dioxopyrrolidin-1-yl) N-Methyl-N-nitrosocarbaMate

There total 1 articles about (2,5-dioxopyrrolidin-1-yl) N-Methyl-N-nitrosocarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,5-dioxopyrrolidin-1-yl methylcarbamate (18342-66-0) → N-methyl-N-nitrosocarbamic acid N'-hydroxysuccinimide ester (80354-48-9)

Guidance literature:

With pyridine; nitrosylchloride; at -20 ℃; for 0.5h;

DOI:10.1021/jm00344a017

Reference yield: 72.0%

4-amino-2,2,6,6-tetramethyl-1-piperidine-1-oxyl (14691-88-4,78774-22-8) + N-methyl-N-nitrosocarbamic acid N'-hydroxysuccinimide ester (80354-48-9) → 2,2,6,6-tetramethyl-4-(3-methyl-3-nitrosoureido)piperidine-1-oxyl (83144-39-2)

Guidance literature:

In N,N-dimethyl-formamide; at 0 ℃; for 1h;

DOI:10.1007/BF00698442

upstream raw materials:

2,5-dioxopyrrolidin-1-yl methylcarbamate

Downstream raw materials:

2,2,6,6-tetramethyl-4-(3-methyl-3-nitrosoureido)piperidine-1-oxyl

Refernces

• 1、 Martinez, Jean,Oiry, Joel,Imbach, Jean Louis,Winternitz, Francois. "Activated N-Nitrosocarbamates for Regioselective Synthesis of N-Nitrosoureas". . p. 178 - 182. Retrieved 2007/10/02.