CARBOXY-PTIO

Base Information

• Chemical Name: CARBOXY-PTIO
• CAS No.: 148819-94-7
• Molecular Formula: C14H17 N2 O4 . K
• Molecular Weight: 317.406
• Hs Code.: 2918999090
• Mol file: 148819-94-7.mol

Synonyms:1H-Imidazol-1-yloxy,2-(4-carboxyphenyl)-4,5-dihydro-4,4,5,5-tetramethyl-, 3-oxide, potassium salt(9CI)

Chemical Property of CARBOXY-PTIO

Chemical Property:

• Appearance/Colour: odorless blue Powder
• Melting Point: 141-143°C
• Boiling Point: 456.3 °C at 760 mmHg
• Flash Point: 229.7 °C
• PSA: 69.29000
• Density: g/cm³
• LogP: 1.86920
• Storage Temp.: 2-8°C
• Solubility.: H2O: >20 mg/mL
• Water Solubility.: Soluble in water. Also soluble in ethanol, methanol, DMSO or DMF.

Purity/Quality:

98%,99%, ^*data from raw suppliers

Carboxy-PTIO potassium salt ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: A nitric oxide (NO) scavenger.? Carboxy-PTIO (148819-94-7) reacts with NO with 1:1 stoichiometry1 producing NO2–/NO3–.?? In LPS-induced endotoxin shock, carboxy-PTIO reversed hypotension and renal dysfunction and increased survival in a rat model.2 A very useful tool for probing the involvement of NO in physiological processes.3,4
• Uses: A water soluble, stable organic free radical that reacts stoichiometrically with NO. Carboxy-PTIO converts NO to NO2 and does not dramatically affect other NO related metabolites. This scavenger allows for the specific investigation of the effect of NO. Carboxy-PTIO is a NO scavenger. It reacts stoichiometrically with NO and can be used for EPR detection of NO. Carboxy-PTIO potassium salt has been used to check the generation of hydroxyl radicals or nitric in reaction mixtures to examine the generation of nitric oxide in reaction mixture. It has also been added to neurons to analyse its effect on glucose/oxygen/serum deprivation (GOSD) condition(4)