N-(2-CYANOETHYL)-PHTHALIMIDE

Base Information

• Chemical Name: N-(2-CYANOETHYL)-PHTHALIMIDE
• CAS No.: 3589-45-5
• Molecular Formula: C11H8 N2 O2
• Molecular Weight: 200.197
• Hs Code.: 2926909090
• Mol file: 3589-45-5.mol

Synonyms:Phthalimide,N-(2-cyanoethyl)- (6CI,7CI,8CI); 1,3-Dioxo-2-isoindolinepropionitrile;3-Phthalimidopropionitrile; N-(2-Cyanoethyl)phthalimide; NSC 525246; b-Phthalimidopropionitrile

Chemical Property of N-(2-CYANOETHYL)-PHTHALIMIDE

Chemical Property:

• Vapor Pressure: 2.65E-06mmHg at 25°C
• Melting Point: 147-148 °C
• Boiling Point: 390.4°Cat760mmHg
• PKA: -2.39±0.20(Predicted)
• Flash Point: 189.9°C
• PSA: 61.17000
• Density: 1.334g/cm³
• LogP: 1.13418

Purity/Quality:

98%min ^*data from raw suppliers

3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanenitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-CYANOETHYL)-PHTHALIMIDE

There total 3 articles about N-(2-CYANOETHYL)-PHTHALIMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phthalic anhydride (85-44-9) + 2-cyanoethylamine (151-18-8,60585-38-8) → 3-phthalimidopropionitrile (3589-45-5)

Guidance literature:

at 190 ℃;

DOI:10.1021/ja01194a024 DOI:10.1021/ja01194a025

Reference yield:

phthalic anhydride (85-44-9) → 3-phthalimidopropionitrile (3589-45-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 2-methyl-pentanone-⁽⁴⁾

2: 200 °C

With 2-methylvaleraldehyde;

DOI:10.1021/ja01194a025

Reference yield:

phthalic anhydride (85-44-9) + 3,3'-Iminodipropionitrile (111-94-4) → 3-phthalimidopropionitrile (3589-45-5)

Guidance literature:

at 200 ℃;

DOI:10.1021/ja01194a025

upstream raw materials:

phthalic anhydride

2-cyanoethylamine

3,3'-Iminodipropionitrile

Downstream raw materials:

2-[2-(2-Phenyl-2H-[1,2,4]triazol-3-yl)-ethyl]-isoindole-1,3-dione

2-{2-[2-(4-Methoxy-phenyl)-2H-[1,2,4]triazol-3-yl]-ethyl}-isoindole-1,3-dione

2-{2-[2-(4-Nitro-phenyl)-2H-[1,2,4]triazol-3-yl]-ethyl}-isoindole-1,3-dione

2-cyanoethylamine